PTPN23 and DDX24

Data Source:
HPRD (two hybrid)

		PTPN23	DDX24
Description		protein tyrosine phosphatase non-receptor type 23	DEAD-box helicase 24
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Endosome Early Endosome Cytosol Nuclear Body Ciliary Basal Body Intracellular Membrane-bounded Organelle Extracellular Exosome	Nucleolus Membrane
	Molecular Function	Protein Tyrosine Phosphatase Activity Protein Binding Protein Kinase Binding	RNA Binding RNA Helicase Activity ATP Binding
	Biological Process	Negative Regulation Of Epithelial Cell Migration Protein Transport Endocytic Recycling Peptidyl-tyrosine Dephosphorylation Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Early Endosome To Late Endosome Transport Cilium Assembly Positive Regulation Of Wnt Protein Secretion Cellular Response To Cytokine Stimulus Positive Regulation Of Homophilic Cell Adhesion Positive Regulation Of Adherens Junction Organization Positive Regulation Of Early Endosome To Late Endosome Transport	RNA Metabolic Process
Pathways		Interleukin-37 signaling
Drugs
Diseases
GWAS		C-reactive protein levels ( 30388399) Refractive error ( 32231278) Type 2 diabetes (adjusted for BMI) ( 29632382)	Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder ( 26184070) Post bronchodilator FEV1/FVC ratio ( 26634245)
Interacting Genes		11 interacting genes: ALG2 CEP19 CEP55 CHMP4B DDX24 LRRK2 NOTCH2NLA PSMA3 TRIM27 UBAP1 UBC	34 interacting genes: BCS1L BRCA1 CSNK2A1 EIF3E EP300 FADD GIT1 GLRA2 HSP90AB1 HSPA5 IDO1 ITGB3BP LMNA MDM2 MKS1 MRPL4 NRXN2 PAFAH1B3 PIN1 POLA2 PRF1 PTEN PTPN23 RAE1 SPACA9 SPTAN1 TERF1 TERF2 TERF2IP TMEM9B TPI1 TRDMT1 UBE2I VDAC3
Entrez ID		25930	57062
HPRD ID		05959	05860
Ensembl ID		ENSG00000076201	ENSG00000089737
Uniprot IDs		B4DST5 Q9H3S7	Q9GZR7
PDB IDs		3RAU 5CRU 5CRV 5LM1 5LM2 5MJY 5MJZ 5MK0 5MK1 5MK2 5MK3
Enriched GO Terms of Interacting Partners?
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