MYRIP and RAB27B

Data Source:
BioGRID (two hybrid)

		MYRIP	RAB27B
Description		myosin VIIA and Rab interacting protein	RAB27B, member RAS oncogene family
Image		No pdb structure
GO Annotations	Cellular Component	Exocyst Photoreceptor Outer Segment Transport Vesicle Cortical Actin Cytoskeleton Dense Core Granule Melanosome Synapse Perinuclear Region Of Cytoplasm	Late Endosome Golgi Stack Plasma Membrane Apical Plasma Membrane Trans-Golgi Network Transport Vesicle Secretory Granule Platelet Dense Granule Membrane Multivesicular Body Membrane Melanosome Zymogen Granule Membrane Extracellular Exosome Anchored Component Of Synaptic Vesicle Membrane Axon Cytoplasm
	Molecular Function	Actin Binding Protein Binding Zinc Ion Binding Myosin Binding Protein Kinase A Binding	GTPase Activity Protein Binding GTP Binding GDP Binding Protein Domain Specific Binding Myosin V Binding
	Biological Process	Intracellular Protein Transport Positive Regulation Of Insulin Secretion	Platelet Degranulation Melanosome Transport Positive Regulation Of Exocytosis Synaptic Vesicle Endocytosis Multivesicular Body Sorting Pathway Anterograde Axonal Protein Transport
Pathways		Insulin processing	Platelet degranulation RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Acute lymphoblastic leukemia (childhood) ( 23007406) Information processing speed ( 21130836) Rapid automised naming of letters ( 30741946) Sleep-related phenotypes ( 17903308) Whole brain grey matter density ( 31530798)	Adult body size ( 32376654) Allergic disease (asthma, hay fever or eczema) ( 29083406) Body mass index ( 28892062) Body size at age 10 ( 32376654) Childhood body mass index ( 26604143) Depression ( 29700475) Serum uric acid levels in response to allopurinol in gout ( 25676789)
Interacting Genes		5 interacting genes: C1orf216 MYO7A OIP5 RAB27A RAB27B	11 interacting genes: DHPS GORASP2 MLPH MYRIP RPH3A RPH3AL SYTL1 SYTL2 SYTL4 SYTL5 UNC13D
Entrez ID		25924	5874
HPRD ID		14796	04846
Ensembl ID		ENSG00000170011	ENSG00000041353
Uniprot IDs		Q8NFW9	O00194
PDB IDs			2F7S
Enriched GO Terms of Interacting Partners?
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