MYRIP and MYO7A

Data Source:
HPRD (in vitro)

		MYRIP	MYO7A
Description		myosin VIIA and Rab interacting protein	myosin VIIA
Image		No pdb structure
GO Annotations	Cellular Component	Exocyst Photoreceptor Outer Segment Transport Vesicle Cortical Actin Cytoskeleton Dense Core Granule Melanosome Synapse Perinuclear Region Of Cytoplasm	Photoreceptor Outer Segment Photoreceptor Inner Segment Cytoplasm Lysosomal Membrane Cytosol Microvillus Cell Cortex Actin Cytoskeleton Apical Plasma Membrane Myosin VII Complex Vesicle Photoreceptor Connecting Cilium Stereocilium Melanosome Synapse Stereocilium Base Upper Tip-link Density
	Molecular Function	Actin Binding Protein Binding Zinc Ion Binding Myosin Binding Protein Kinase A Binding	Microfilament Motor Activity Protein Binding Calmodulin Binding ATP Binding Protein Domain Specific Binding Spectrin Binding Actin-dependent ATPase Activity Identical Protein Binding ADP Binding Protein N-terminus Binding Actin Filament Binding
	Biological Process	Intracellular Protein Transport Positive Regulation Of Insulin Secretion	Phagolysosome Assembly Intracellular Protein Transport Actin Filament Organization Lysosome Organization Sensory Organ Development Visual Perception Sensory Perception Of Sound Actin Filament-based Movement Vesicle Transport Along Actin Filament Cellular Protein Localization Eye Photoreceptor Cell Development Mechanoreceptor Differentiation Post-embryonic Animal Organ Morphogenesis Sensory Perception Of Light Stimulus Equilibrioception Pigment Granule Transport Auditory Receptor Cell Stereocilium Organization
Pathways		Insulin processing	The canonical retinoid cycle in rods (twilight vision)
Drugs
Diseases			Usher syndrome (US) Deafness, autosomal dominant Deafness, autosomal recessive
GWAS		Acute lymphoblastic leukemia (childhood) ( 23007406) Information processing speed ( 21130836) Rapid automised naming of letters ( 30741946) Sleep-related phenotypes ( 17903308) Whole brain grey matter density ( 31530798)	Lewy body disease ( 25188341) Post bronchodilator FEV1/FVC ratio ( 26634245) Tourette syndrome ( 30818990)
Interacting Genes		5 interacting genes: C1orf216 MYO7A OIP5 RAB27A RAB27B	12 interacting genes: ACTA1 CALM1 CDH23 KEAP1 KHDRBS1 LINC00839 MAP2 MYRIP PRKAR1A USH1C VEZT WHRN
Entrez ID		25924	4647
HPRD ID		14796	02043
Ensembl ID		ENSG00000170011	ENSG00000137474
Uniprot IDs		Q8NFW9	Q13402
PDB IDs			5MV9
Enriched GO Terms of Interacting Partners?
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