IFFO1 and NDN

Data Source:
BioGRID (two hybrid)

		IFFO1	NDN
Description		intermediate filament family orphan 1	necdin, MAGE family member
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Intermediate Filament Nuclear Matrix Site Of Double-strand Break	Nucleoplasm Centrosome Cytosol Protein-containing Complex Cell Projection Perikaryon
	Molecular Function	Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Gamma-tubulin Binding Promoter-specific Chromatin Binding
	Biological Process	Double-strand Break Repair Via Nonhomologous End Joining Protein Localization To Site Of Double-strand Break DNA Double-strand Break Attachment To Nuclear Envelope	Negative Regulation Of Transcription By RNA Polymerase II Neuron Migration Respiratory System Process Axonal Fasciculation Central Nervous System Development Negative Regulation Of Cell Population Proliferation Glial Cell Migration Post-embryonic Development Cytokine-mediated Signaling Pathway Sensory Perception Of Pain Regulation Of Growth Negative Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of Transcription By RNA Polymerase II Neurotrophin TRK Receptor Signaling Pathway Axon Extension Multicellular Organismal Homeostasis Genetic Imprinting Positive Regulation Of Protein Deacetylation
Pathways			Interleukin-4 and Interleukin-13 signaling
Drugs
Diseases			Prader-Willi and Angelman syndromes, including: Angelman syndrome (AS); Prader-Willi syndrome (PWS)
GWAS		Waist-to-hip ratio adjusted for BMI ( 28552196)	Body size at age 10 ( 32376654) Depressive symptoms (SSRI exposure interaction) ( 25649181) HDL cholesterol levels ( 32203549) Plasma anti-thyroid peroxidase levels ( 29678681) Serum metabolite concentrations in chronic kidney disease ( 29545352)
Interacting Genes		8 interacting genes: ACAP1 GFI1B LMNA NDN RHOU RNF183 TCHP XRCC4	47 interacting genes: APBB1IP ARSL BLOC1S6 CALCOCO2 CCDC136 CDR2 DTNBP1 E2F1 E2F4 EEF1AKMT1 EGFR EID1 EPAS1 FAM131C FSD2 FXR2 GKAP1 GOLGA2 HIF1A HNRNPU IFFO1 IL1A IL32 IRS4 LAX1 LPXN MIER2 MKRN2 MYG1 NEFL NGFR NUBP1 NUCB1 NUCB2 P4HA3 PALS2 PJA1 PPARGC1A PPFIA1 SERTAD3 SIRT1 SSX2IP TFIP11 TP53 U2AF1 ZBTB1 ZBTB7B
Entrez ID		25900	4692
HPRD ID		09988	03667
Ensembl ID		ENSG00000010295	ENSG00000182636
Uniprot IDs		A0A087WZ16 B4DQQ1 Q0D2I5 Q6P593 Q9Y4M3	Q99608 X5D982
PDB IDs		6ABO
Enriched GO Terms of Interacting Partners?
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