NDN and NUBP1

Data Source:
HPRD (two hybrid)

		NDN	NUBP1
Description		necdin, MAGE family member	nucleotide binding protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Centrosome Cytosol Protein-containing Complex Cell Projection Perikaryon	Nucleus Centriole Cytosol Plasma Membrane Cilium
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Gamma-tubulin Binding Promoter-specific Chromatin Binding	Nucleotide Binding Protein Binding ATP Binding Metal Ion Binding Iron-sulfur Cluster Binding 4 Iron, 4 Sulfur Cluster Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Neuron Migration Respiratory System Process Axonal Fasciculation Central Nervous System Development Negative Regulation Of Cell Population Proliferation Glial Cell Migration Post-embryonic Development Cytokine-mediated Signaling Pathway Sensory Perception Of Pain Regulation Of Growth Negative Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of Transcription By RNA Polymerase II Neurotrophin TRK Receptor Signaling Pathway Axon Extension Multicellular Organismal Homeostasis Genetic Imprinting Positive Regulation Of Protein Deacetylation	Regulation Of Cell Growth Cellular Iron Ion Homeostasis Negative Regulation Of Centrosome Duplication Iron-sulfur Cluster Assembly Cell Projection Organization Centrosome Localization Protein Localization To Cell Cortex
Pathways		Interleukin-4 and Interleukin-13 signaling	Cytosolic iron-sulfur cluster assembly
Drugs
Diseases		Prader-Willi and Angelman syndromes, including: Angelman syndrome (AS); Prader-Willi syndrome (PWS)
GWAS		Body size at age 10 ( 32376654) Depressive symptoms (SSRI exposure interaction) ( 25649181) HDL cholesterol levels ( 32203549) Plasma anti-thyroid peroxidase levels ( 29678681) Serum metabolite concentrations in chronic kidney disease ( 29545352)	Cerebrospinal AB1-42 levels in normal cognition ( 29274321)
Interacting Genes		47 interacting genes: APBB1IP ARSL BLOC1S6 CALCOCO2 CCDC136 CDR2 DTNBP1 E2F1 E2F4 EEF1AKMT1 EGFR EID1 EPAS1 FAM131C FSD2 FXR2 GKAP1 GOLGA2 HIF1A HNRNPU IFFO1 IL1A IL32 IRS4 LAX1 LPXN MIER2 MKRN2 MYG1 NEFL NGFR NUBP1 NUCB1 NUCB2 P4HA3 PALS2 PJA1 PPARGC1A PPFIA1 SERTAD3 SIRT1 SSX2IP TFIP11 TP53 U2AF1 ZBTB1 ZBTB7B	3 interacting genes: NDN SPRY2 TENM1
Entrez ID		4692	4682
HPRD ID		03667	02611
Ensembl ID		ENSG00000182636	ENSG00000103274
Uniprot IDs		Q99608 X5D982	P53384
PDB IDs
Enriched GO Terms of Interacting Partners?
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