HECTD1 and IGSF1

		HECTD1	IGSF1
Description		HECT domain E3 ubiquitin protein ligase 1	immunoglobulin superfamily member 1
Image			No pdb structure
GO Annotations	Cellular Component		Extracellular Region Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding Coreceptor Activity Inhibin Binding Activin Receptor Antagonist Activity
	Biological Process	Heart Valve Development Ventricular Septum Development Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Aorta Development Anatomical Structure Development Protein K63-linked Ubiquitination	Regulation Of Transcription, DNA-templated Negative Regulation Of Activin Receptor Signaling Pathway
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Age at voice drop ( 27182965) Menarche (age at onset) ( 27182965)
Interacting Genes		8 interacting genes: HRAS HSPB1 IGSF1 MTNR1B UBE2D2 UBE2D3 UBE2L3 YWHAG	8 interacting genes: ACVR1 ACVR1B ACVR2A ACVR2B HECTD1 IGF1 INHBB RANBP10
Entrez ID		25831	3547
HPRD ID		17098	02138
Ensembl ID		ENSG00000092148	ENSG00000147255
Uniprot IDs		Q9ULT8	Q8N6C5
PDB IDs		2DK3 2LC3 3DKM
Enriched GO Terms of Interacting Partners?
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