RBFOX1 and HSFY1

Data Source:
BioGRID (two hybrid)

		RBFOX1	HSFY1
Description		RNA binding fox-1 homolog 1	heat shock transcription factor Y-linked 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Trans-Golgi Network Cytoplasmic Stress Granule Nuclear Stress Granule	Chromatin Nucleus Cytoplasm
	Molecular Function	RNA Binding MRNA Binding Protein Binding Protein C-terminus Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing Nervous System Development RNA Splicing RNA Transport	Regulation Of Transcription By RNA Polymerase II
Pathways		MECP2 regulates transcription factors
Drugs
Diseases
GWAS		3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Adult body size ( 32376654) Adverse response to inhaled corticosteroid treatment x age interaction in asthma ( 32119686) Albumin-globulin ratio ( 29403010) Allergic rhinitis ( 25085501) anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Bitter alcoholic beverage consumption ( 31046077) Bitter non-alcoholic beverage consumption ( 31046077) Body mass index ( 28892062 25673413) Brain glucose metabolism (fluorodeoxyglucose uptake) ( 30596066) Brain volume in infants (cerebrospinal fluid) ( 28763065) Cerebellum white matter volume ( 31530798) Chronotype ( 30696823) Cocaine dependence ( 31212010) Cognitive decline rate in late mild cognitive impairment ( 26252872) Depression ( 29700475) Evening vs. morning chronotype (sMEQ score) ( 32579418) Extraversion ( 27918536) Feeling worry ( 29500382) General cognitive ability ( 29844566) General risk tolerance (MTAG) ( 30643258) Glaucoma ( 25027321) High myopia ( 31816047) Hydrolysed wheat protein allergy ( 31301374) Hyperopia ( 25233373) Insomnia symptoms (never/rarely vs. usually) ( 30804566) Intelligence (MTAG) ( 29326435) Intracranial aneurysm ( 29531279) Major depressive disorder ( 27479909 29728651) Mental health study participation (completed survey) ( 31263887) Metabolite levels ( 31628463) Myopia ( 27182965 25233373) Neurociticism ( 29500382) Neurofibrillary tangles ( 31497858) Neuroticism ( 29255261) Nickel levels ( 26025379) Obesity (extreme) ( 31852448) Obesity-related traits ( 23251661) Optic disc size ( 31809533) Photic sneeze reflex ( 27182965) Pit-and-Fissure caries ( 24556642) Refractive astigmatism ( 30306274) Refractive error ( 23396134 32231278 23474815) Renal cell carcinoma ( 31231134) Rheumatoid arthritis ( 30423114) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Systemising ( 31508503) Systolic blood pressure ( 30224653) Type 1 diabetes autoantibodies in high risk HLA genotype individuals (time to event) ( 29310926) Type 2 diabetes ( 30130595) Worry too long after an embarrassing experience ( 29500382)
Interacting Genes		49 interacting genes: AGR2 ALG13 ARID5A ATN1 ATXN1 ATXN1L ATXN2 BHLHE40 C1orf94 CELF3 CRX DAB1 DAZAP2 DMRTB1 DVL2 FAM168A GCA HNRNPF HSFX1 HSFY1 HYPK KIFAP3 LASP1 LZTS2 MAGED1 NOC2L NUMBL P4HA3 PCBP4 POGZ PRR20A PRRC2A PSMF1 QKI RBFOX2 RBFOX3 RBM24 RBM47 RBPMS RBPMS2 RHOXF2 SIRPB1 SNRPN STRBP TEX37 TNIP1 TOLLIP UBL3 VENTX	20 interacting genes: ATXN1 BANP BPIFA1 CCNK DTX2 GCM2 HGS HNRNPF JAK2 NFYC OTUD7B QRICH1 RBFOX1 RBM47 RBPMS SMARCB1 SOX15 SV2B TBX6 TOX2
Entrez ID		54715	86614
HPRD ID		16091	11850
Ensembl ID		ENSG00000078328	ENSG00000172468
Uniprot IDs		A0A6Q8PH77 B7Z1U7 Q59HD3 Q9NWB1 X5D7T5 X5DNY3 X5DP44	Q96LI6
PDB IDs		2ERR 2N82 4ZKA
Enriched GO Terms of Interacting Partners?
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