NUTM1 and LRRC8E

Data Source:
BioGRID (two hybrid)

		NUTM1	LRRC8E
Description		NUT midline carcinoma family member 1	leucine rich repeat containing 8 VRAC subunit E
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Cytoplasm Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Plasma Membrane Ion Channel Complex
	Molecular Function	Protein Binding	Volume-sensitive Anion Channel Activity Protein Binding
	Biological Process		Inorganic Anion Transport Aspartate Transmembrane Transport Transmembrane Transport Cellular Response To Osmotic Stress Anion Transmembrane Transport
Pathways			Miscellaneous transport and binding events
Drugs
Diseases			Agammaglobulinemias, including the following six diseases: X-linked agammaglobulinemia (Bruton's agammaglobulinemia, XLA); IgM heavy chain gene deletions; Ig-alpha defect; Autosomal recessive agammaglobulinaemia; B cell-linker protein (BLNK) deficiency; Leucine-rich repeat-containing 8
GWAS
Interacting Genes		54 interacting genes: ALOX5 AQP1 ARHGEF6 AXIN1 C2CD6 CCDC116 CCDC185 CCHCR1 CDC20B CDK18 CHCHD3 ENKD1 FAM161A GADD45GIP1 GPANK1 HSPBAP1 IFIT2 KANK2 KANSL1 KPNA2 LHX8 LMO1 LMO2 LMO3 LRRC8E MBD3 METTL17 MORN4 NEBL OSTF1 P4HA3 PLEKHF2 PRKAA2 PRKAB2 PRPF18 PSME4 RCOR3 RIC8A SAMD4A SAMD4B SCNM1 SH2D1B SH2D4A SMARCD1 SOGA1 TBC1D21 TEAD4 TLE5 TP53BP2 TSGA10IP TTC23 TXN2 ZMYND10 ZNF277	7 interacting genes: FBXO7 GPSM2 LNX2 NUTM1 SAMD4B TRIM2 TRIM3
Entrez ID		256646	80131
HPRD ID		10606	08670
Ensembl ID		ENSG00000184507	ENSG00000171017
Uniprot IDs		Q86Y26	Q6NSJ5
PDB IDs
Enriched GO Terms of Interacting Partners?
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