LRRC8E and SAMD4B

Data Source:
BioGRID (two hybrid)

		LRRC8E	SAMD4B
Description		leucine rich repeat containing 8 VRAC subunit E	sterile alpha motif domain containing 4B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Plasma Membrane Ion Channel Complex	P-body Nucleus Cytosol
	Molecular Function	Volume-sensitive Anion Channel Activity Protein Binding	RNA Binding MRNA Binding Protein Binding Translation Repressor Activity
	Biological Process	Inorganic Anion Transport Aspartate Transmembrane Transport Transmembrane Transport Cellular Response To Osmotic Stress Anion Transmembrane Transport	Nuclear-transcribed MRNA Poly(A) Tail Shortening Negative Regulation Of Translation Regulation Of MRNA Stability
Pathways		Miscellaneous transport and binding events
Drugs
Diseases		Agammaglobulinemias, including the following six diseases: X-linked agammaglobulinemia (Bruton's agammaglobulinemia, XLA); IgM heavy chain gene deletions; Ig-alpha defect; Autosomal recessive agammaglobulinaemia; B cell-linker protein (BLNK) deficiency; Leucine-rich repeat-containing 8
GWAS			Obesity-related traits ( 23251661)
Interacting Genes		7 interacting genes: FBXO7 GPSM2 LNX2 NUTM1 SAMD4B TRIM2 TRIM3	7 interacting genes: BCL2L10 CCDC179 LRRC8E NUTM1 RSRC2 USP53 YWHAG
Entrez ID		80131	55095
HPRD ID		08670	10960
Ensembl ID		ENSG00000171017	ENSG00000179134
Uniprot IDs		Q6NSJ5	A0A024R0N7 M0QZ22 Q5PRF9 Q66K25 Q8IXP7
PDB IDs
Enriched GO Terms of Interacting Partners?
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