LCE5A and ALPP

Data Source:
BioGRID (two hybrid)

		LCE5A	ALPP
Description		late cornified envelope 5A	alkaline phosphatase, placental
Image		No pdb structure
GO Annotations	Cellular Component		Plasma Membrane Cell Surface Integral Component Of Membrane Anchored Component Of Membrane
	Molecular Function	Protein Binding Identical Protein Binding	Magnesium Ion Binding Alkaline Phosphatase Activity Protein Binding Zinc Ion Binding
	Biological Process	Keratinization	Dephosphorylation
Pathways		Formation of the cornified envelope	Intra-Golgi traffic
Drugs			Calcium METHYL-PHOSPHONIC ACID MONO-(4-NITRO-PHENYL) ESTER
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Atopic march ( 26542096) Hair morphology ( 19896111) Inflammatory skin disease ( 25574825)	Blood protein levels ( 30072576) Height ( 19570815) Refractive error ( 32231278)
Interacting Genes		66 interacting genes: ADAM12 ALPP CHIC2 CHRD CREB5 CYP21A2 CYSRT1 FBLN1 HOXA1 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP12-4 KRTAP21-2 KRTAP3-1 KRTAP4-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-9 KRTAP6-2 KRTAP6-3 KRTAP9-2 KRTAP9-3 LCE1A LCE1B LCE1C LCE1E LCE1F LCE2B LCE2C LCE4A NBPF19 NECTIN2 NOTCH2NLA NTAQ1 NUTF2 PLAC8 PLSCR2 PLSCR3 PLSCR4 POU4F2 RGS17 RGS20 RNF4 SLC39A7 SMCP SPRED2 SPRY1 TRIM42 UBE2I VWC2L ZNF655	42 interacting genes: ADAMTSL4 ALPG CRCT1 CREB5 CXCL5 CYSRT1 FBXO34 GEMIN4 GPLD1 GSC2 HOXA1 IGFBP6 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP10-8 KRTAP4-12 KRTAP5-9 LATS1 LCE1D LCE1E LCE1F LCE2C LCE3A LCE3B LCE3C LCE3D LCE3E LCE5A LELP1 MEOX2 NBPF19 NLGN3 NOTCH2NLA NR4A3 OTX1 PIGK POU4F2 RGS19 RGS20 SMCP TGM1
Entrez ID		254910	250
HPRD ID		17265	01379
Ensembl ID		ENSG00000186207	ENSG00000163283
Uniprot IDs		Q5TCM9	B2R7C7 P05187
PDB IDs			1EW2 1ZEB 1ZED 1ZEF 2GLQ 3MK0 3MK1 3MK2
Enriched GO Terms of Interacting Partners?
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