ARHGAP8 and BNIP2

Data Source:
HPRD (in vivo, in vitro)

		ARHGAP8	BNIP2
Description		Rho GTPase activating protein 8	BCL2 interacting protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol	Nuclear Envelope Cytoplasm Cytosol Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm
	Molecular Function	GTPase Activator Activity Protein Binding	Exopolyphosphatase Activity GTPase Activator Activity Calcium Ion Binding Protein Binding
	Biological Process	Signal Transduction Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of ERK1 And ERK2 Cascade	Polyphosphate Catabolic Process Apoptotic Process Negative Regulation Of Apoptotic Process Positive Regulation Of GTPase Activity Positive Regulation Of Muscle Cell Differentiation
Pathways		Rho GTPase cycle	Myogenesis Myogenesis
Drugs
Diseases
GWAS		Binge eating behaviour in bipolar disorder ( 29391396) Body mass index ( 28552196) Electroencephalographic traits in alcoholism ( 22554406) Non-alcoholic fatty liver disease activity score in non-alcoholic fatty liver disease ( 31311600) Weight ( 28552196)	Gut microbiota (bacterial taxa) ( 27723756)
Interacting Genes		6 interacting genes: BNIP2 CTTN CYGB RHOA SH3GL1 ZMYND12	56 interacting genes: ABHD4 AGPAT3 APOBEC3B ARHGAP1 ARHGAP8 BCL2 BNIP3 BNIP5 BNIPL CDC42 CHODL CPLX4 CREB3 CYB5R3 DESI2 DGAT2L6 DHRS1 EI24 ERLIN1 FAHD1 FAM209A FAM3C FATE1 FGFR1 FRK GORAB GPR152 GPX8 GRAMD2A GSC2 HSPA1B KCNK5 KLC1 LDLRAD1 LIME1 LMNA MEOX1 MEOX2 MYO5B NCBP1 OTX2 PEX12 PLEKHO1 RASGRP4 SFT2D2 SIN3A SLC35E3 SLC39A9 SLC7A14 SYT1 SYT2 TMEM237 TMPRSS2 TMX2 UPK1B YIF1A
Entrez ID		23779	663
HPRD ID		06448	04481
Ensembl ID		ENSG00000241484	ENSG00000140299
Uniprot IDs		P85298 Q6PJW1	J3KN59 Q12982
PDB IDs
Enriched GO Terms of Interacting Partners?
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