BNIP2 and ERLIN1

Data Source:
BioGRID (two hybrid)

		BNIP2	ERLIN1
Description		BCL2 interacting protein 2	ER lipid raft associated 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Cytoplasm Cytosol Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Protein-containing Complex
	Molecular Function	Exopolyphosphatase Activity GTPase Activator Activity Calcium Ion Binding Protein Binding	Protein Binding Cholesterol Binding Ubiquitin Protein Ligase Binding
	Biological Process	Polyphosphate Catabolic Process Apoptotic Process Negative Regulation Of Apoptotic Process Positive Regulation Of GTPase Activity Positive Regulation Of Muscle Cell Differentiation	Cholesterol Metabolic Process Ubiquitin-dependent ERAD Pathway SREBP Signaling Pathway Negative Regulation Of Cholesterol Biosynthetic Process Negative Regulation Of Fatty Acid Biosynthetic Process Transmembrane Transport
Pathways		Myogenesis Myogenesis	ABC-family proteins mediated transport Defective CFTR causes cystic fibrosis
Drugs
Diseases
GWAS		Gut microbiota (bacterial taxa) ( 27723756)	Apolipoprotein A1 levels ( 32203549) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) General cognitive ability ( 29844566) HDL cholesterol ( 30275531) HDL cholesterol levels ( 32203549) Heel bone mineral density ( 30598549) Liver enzyme levels ( 18940312) Refractive error ( 32231278) Response to radiotherapy in cancer (late toxicity) ( 24785509) Squamous cell lung carcinoma ( 28604730) Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)
Interacting Genes		56 interacting genes: ABHD4 AGPAT3 APOBEC3B ARHGAP1 ARHGAP8 BCL2 BNIP3 BNIP5 BNIPL CDC42 CHODL CPLX4 CREB3 CYB5R3 DESI2 DGAT2L6 DHRS1 EI24 ERLIN1 FAHD1 FAM209A FAM3C FATE1 FGFR1 FRK GORAB GPR152 GPX8 GRAMD2A GSC2 HSPA1B KCNK5 KLC1 LDLRAD1 LIME1 LMNA MEOX1 MEOX2 MYO5B NCBP1 OTX2 PEX12 PLEKHO1 RASGRP4 SFT2D2 SIN3A SLC35E3 SLC39A9 SLC7A14 SYT1 SYT2 TMEM237 TMPRSS2 TMX2 UPK1B YIF1A	7 interacting genes: AGR3 BNIP2 FA2H RBFA SEC22A SEC23A TMEM199
Entrez ID		663	10613
HPRD ID		04481	08502
Ensembl ID		ENSG00000140299	ENSG00000107566
Uniprot IDs		J3KN59 Q12982	O75477
PDB IDs
Enriched GO Terms of Interacting Partners?
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