LDOC1 and RPP25

Data Source:
BioGRID (two hybrid)

		LDOC1	RPP25
Description		LDOC1 regulator of NFKB signaling	ribonuclease P and MRP subunit p25
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus	Ribonuclease MRP Complex Nucleoplasm Nucleolus Multimeric Ribonuclease P Complex Centriolar Satellite
	Molecular Function	Protein Binding	RNA Binding Ribonuclease P Activity Protein Binding Ribonuclease P RNA Binding
	Biological Process	Negative Regulation Of Cell Population Proliferation Cellular Response To Lipopolysaccharide Cellular Response To Muramyl Dipeptide	TRNA 5'-leader Removal RRNA Processing RNA Phosphodiester Bond Hydrolysis, Endonucleolytic
Pathways			tRNA processing in the nucleus Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS			Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
Interacting Genes		107 interacting genes: AATF ABLIM1 AEBP2 AP1M1 AQP1 ATF4 ATP6V1G1 BARD1 BEX2 BYSL C1orf109 CCDC33 CCDC85B CDC5L CEBPE CFAP53 CTNNBL1 DPF2 DPPA4 ENKD1 FAM107A FAM110A FAM161A FAM193B FAM50B FAM90A1 FCHSD2 FOSL1 FXR2 GADD45GIP1 GNL3L GPANK1 HAUS1 HDAC4 HGS HOXB5 HOXC8 IKZF3 IKZF5 INPP1 IQCB1 JRK KRT15 KRT18 LATS1 LENG1 LMO2 LNX1 MBD3 MEAF6 MFAP1 MSGN1 MYC MZF1 NOD2 NRIP1 NXF1 PEG10 PLEKHF2 POLL PPP1R18 PRPF18 PRPF31 PSMA1 PSMF1 RAB29 RALBP1 RASSF10 RIBC1 RNF6 RPP25 SCNM1 SDCBP SETD5 SH2D4A SMARCB1 SMARCD1 SUDS3 TASOR2 TBC1D7 TCEANC TEAD4 THAP7 TLE5 TMSB4XP1 TNNT1 TSGA10IP TSNAX TTC23 UBTFL1 UTP14A WDR25 WT1 ZBTB16 ZBTB24 ZFP1 ZGPAT ZNF124 ZNF250 ZNF408 ZNF564 ZNF587 ZNF629 ZNF648 ZNF688 ZNF774 ZNF835	22 interacting genes: ABI2 BACH2 BANP DDI1 HOMEZ KRT15 LDOC1 LRRC73 PDLIM7 PICK1 PNMA1 POP1 POP4 POP5 POP7 RBPMS RPP14 RPP38 SAT1 SF3B4 TERF2IP ZNF438
Entrez ID		23641	54913
HPRD ID		02322	15276
Ensembl ID		ENSG00000182195	ENSG00000178718
Uniprot IDs		O95751	Q9BUL9
PDB IDs			6AHR 6AHU 6CWX
Enriched GO Terms of Interacting Partners?
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