PPP1R1C and TNPO3

Data Source:
BioGRID (two hybrid)

		PPP1R1C	TNPO3
Description		protein phosphatase 1 regulatory inhibitor subunit 1C	transportin 3
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Nuclear Envelope Annulate Lamellae Cytoplasm Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Phosphatase Inhibitor Activity Protein Binding	Protein Binding Small GTPase Binding Identical Protein Binding Nuclear Import Signal Receptor Activity
	Biological Process	Cell Cycle Negative Regulation Of Phosphoprotein Phosphatase Activity Intracellular Signal Transduction Cell Division	Protein Import Into Nucleus
Pathways
Drugs
Diseases
GWAS		Hip circumference adjusted for BMI ( 28552196) Systolic blood pressure ( 30578418)	Diffuse cutaneous systemic sclerosis ( 29293537) Limited cutaneous systemic scleroderma ( 29293537) Platelet count ( 32888494) Plateletcrit ( 32888494) Primary biliary cholangitis ( 20639880) Primary biliary cirrhosis ( 22961000) SjÃ¶gren's syndrome ( 24097067) Systemic lupus erythematosus ( 18204446 24871463 26606652 23053960 26502338 18204098 28714469) Systemic lupus erythematosus and Systemic sclerosis ( 23740937) Systemic lupus erythematosus or rheumatoid arthritis ( 27193031) Systemic sclerosis ( 21750679 31672989 30247649 29293537) Systemic sclerosis (anti-centromere-positive) ( 29293537) Systemic sclerosis (anti-topoisomerase-positive) ( 29293537) Systemic seropositive rheumatic diseases (Systemic sclerosis or systemic lupus erythematosus or rheumatoid arthritis or idiopathic inflammatory myopathies) ( 30573655) Ulcerative colitis ( 23128233 21297633)
Interacting Genes		1 interacting genes: TNPO3	19 interacting genes: BLMH CAMK2B CAMK2D CAMK2G CHMP3 CLPP ECI2 GCH1 ICA1L KRT75 KRTAP10-8 MEOX2 NME1 PPP1R1C SMURF2 SRSF1 SSX2 SSX2B TRA2B
Entrez ID		151242	23534
HPRD ID		15169	18209
Ensembl ID		ENSG00000150722	ENSG00000064419
Uniprot IDs		Q8WVI7	A0A024R794 B3KMX1 Q9Y5L0
PDB IDs			4C0O 4C0P 4C0Q 4OL0 6GX9
Enriched GO Terms of Interacting Partners?
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