ITGB3BP and PIH1D2

Data Source:
BioGRID (two hybrid, two hybrid)

		ITGB3BP	PIH1D2
Description		integrin subunit beta 3 binding protein	PIH1 domain containing 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Condensed Chromosome Kinetochore Nucleus Nucleoplasm Cytoplasm Cytosol Membrane	Cytoplasm R2TP Complex Ribonucleoprotein Complex
	Molecular Function	Protein Binding Protein C-terminus Binding	Protein Binding Small GTPase Binding
	Biological Process	Regulation Of Transcription, DNA-templated Apoptotic Process Cell Cycle Cell Adhesion Signal Transduction CENP-A Containing Nucleosome Assembly Positive Regulation Of Apoptotic Process Cell Division	Box C/D SnoRNP Assembly RRNA Processing
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal NRIF signals cell death from the nucleus NRIF signals cell death from the nucleus Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Mean spheric corpuscular volume ( 32888494)	Brain morphology (MOSTest) ( 32665545)
Interacting Genes		41 interacting genes: ACTN2 ANKRD11 APP ARFIP2 C14orf119 CCNA2 CERT1 DDX24 EFHC1 ESR1 GTPBP3 HSF2BP ITGB3 ITGB5 KDM1A KIAA0930 KIFC3 LRRK2 MAPK6 MAPK9 MEIS2 MEOX2 MSGN1 MTA1 NFKB1 NRDE2 NTAQ1 PBX3 PIH1D2 PIK3R3 RECQL5 RXRA RXRG SNAPC5 SUOX SVIL THRA TRIML2 UBR7 USHBP1 USP20	69 interacting genes: ANKRD11 BAG3 BANP CBLL2 CBX8 CCNL2 CDC23 CDCA8 CDKL3 CFAP206 COMMD3 CT55 CTAG1A CTAG1B DES DPH3 DSCAM EIF4A2 EXOSC5 FRS3 GFAP GMCL1 GPRASP2 HES7 HSF4 IGF2BP3 IQUB ITGB3BP KRTAP12-2 KRTAP12-4 LAP3 LMNB1 MCCD1 MDFI MED20 MISP MRFAP1L1 MVP NFIL3 NHSL2 NOTO NTAQ1 NXF1 PBX4 PLEKHJ1 POLR1C PRDM6 PRMT3 RALA REL RSPO4 SDCBP SERTAD1 SLPI SPRED1 SSX3 SUOX TAF6 TASOR2 TBATA TCEA2 TNNI1 TTC23 ZBTB1 ZMAT5 ZNF185 ZNF417 ZNF438 ZNF688
Entrez ID		23421	120379
HPRD ID		09267	14021
Ensembl ID		ENSG00000142856	ENSG00000150773
Uniprot IDs		D3DQ59 Q13352	Q8WWB5
PDB IDs
Enriched GO Terms of Interacting Partners?
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