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PIH1D2 and POLR1C
Data Source:
BioGRID
(two hybrid)
PIH1D2
POLR1C
Description
PIH1 domain containing 2
RNA polymerase I and III subunit C
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
R2TP Complex
Ribonucleoprotein Complex
Nucleoplasm
RNA Polymerase III Complex
RNA Polymerase I Complex
Cytosol
Molecular Function
Protein Binding
Small GTPase Binding
RNA Polymerase I Activity
RNA Polymerase III Activity
DNA Binding
DNA-directed 5'-3' RNA Polymerase Activity
Protein Binding
Protein Dimerization Activity
Biological Process
Box C/D SnoRNP Assembly
RRNA Processing
Transcription By RNA Polymerase I
Transcription Initiation From RNA Polymerase I Promoter
Transcription Elongation From RNA Polymerase I Promoter
Termination Of RNA Polymerase I Transcription
Transcription By RNA Polymerase III
Positive Regulation Of Type I Interferon Production
Positive Regulation Of Gene Expression, Epigenetic
Pathways
Cytosolic sensors of pathogen-associated DNA
NoRC negatively regulates rRNA expression
B-WICH complex positively regulates rRNA expression
RNA Polymerase I Transcription Initiation
RNA Polymerase I Transcription Initiation
RNA Polymerase I Promoter Escape
RNA Polymerase III Chain Elongation
RNA Polymerase I Transcription Termination
RNA Polymerase III Transcription Termination
RNA Polymerase III Abortive And Retractive Initiation
RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase III Transcription Initiation From Type 2 Promoter
RNA Polymerase III Transcription Initiation From Type 2 Promoter
RNA Polymerase III Transcription Initiation From Type 3 Promoter
RNA Polymerase III Transcription Initiation From Type 3 Promoter
Drugs
Diseases
Treacher Collins syndrome
GWAS
Brain morphology (MOSTest) (
32665545
)
GLP-1 levels in response to oral glucose tolerance test (fasting) (
29093273
)
Waist-to-hip ratio adjusted for BMI (
26426971
)
Waist-to-hip ratio adjusted for BMI (age <50) (
26426971
)
Waist-to-hip ratio adjusted for BMI (age >50) (
26426971
)
Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) (
26426971
)
Interacting Genes
69 interacting genes:
ANKRD11
BAG3
BANP
CBLL2
CBX8
CCNL2
CDC23
CDCA8
CDKL3
CFAP206
COMMD3
CT55
CTAG1A
CTAG1B
DES
DPH3
DSCAM
EIF4A2
EXOSC5
FRS3
GFAP
GMCL1
GPRASP2
HES7
HSF4
IGF2BP3
IQUB
ITGB3BP
KRTAP12-2
KRTAP12-4
LAP3
LMNB1
MCCD1
MDFI
MED20
MISP
MRFAP1L1
MVP
NFIL3
NHSL2
NOTO
NTAQ1
NXF1
PBX4
PLEKHJ1
POLR1C
PRDM6
PRMT3
RALA
REL
RSPO4
SDCBP
SERTAD1
SLPI
SPRED1
SSX3
SUOX
TAF6
TASOR2
TBATA
TCEA2
TNNI1
TTC23
ZBTB1
ZMAT5
ZNF185
ZNF417
ZNF438
ZNF688
119 interacting genes:
ADAMTSL4
ARHGEF5
ATRIP
AVPI1
BHLHB9
BIN3
BIRC7
BLZF1
C1orf105
C21orf58
C4orf45
CBX8
CBY2
CCDC33
CCNK
CCT3
CGGBP1
CLU
CORO1A
CORO1B
CRACR2A
EFHC2
EP400
FH
FMR1
FOXR2
GAS8
GMPPB
GOLGA6A
GOLGA6L9
GRPEL1
GSTO2
HDX
HNRNPH1
HOXB9
HOXD12
IHO1
IKZF3
INCA1
KCTD1
KCTD13
KLF15
KRT19
KRT75
KRT76
KRTAP12-2
KRTAP3-1
LNX2
LRIF1
LZTS1
LZTS2
MBIP
MEI4
MEOX2
MKRN3
MORN3
MRPS23
MYD88
MYO5B
NDUFB10
NEDD4
NFKBIB
NIF3L1
NME1
NME4
PIH1D2
POLDIP3
POLR1D
POLR1E
POLR1G
POLR2G
POLR2J
POLR2J3
PPP2R3C
PSMA1
RBM48
RIMBP3
RIMBP3C
RSPH14
RUSC1
SAXO1
SMN1
SMN2
SORBS3
SPATC1L
SPRY1
STMN3
TASOR2
TAX1BP1
TCF4
TEX43
TFIP11
TLE5
TMEM121
TNFAIP1
TNNI1
TRAIP
TRIM14
TRIM27
TRIOBP
TSC22D4
UNKL
USP54
VIM
WASHC1
WRN
XPA
YPEL3
ZBED1
ZBTB42
ZC2HC1C
ZFP57
ZIM2
ZNF547
ZNF554
ZNF655
ZNF688
ZNF835
ZRANB1
Entrez ID
120379
9533
HPRD ID
14021
09661
Ensembl ID
ENSG00000150773
ENSG00000171453
Uniprot IDs
Q8WWB5
O15160
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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