ICOSLG and DIP2A

Data Source:
BioGRID (affinity chromatography technology)

		ICOSLG	DIP2A
Description		inducible T cell costimulator ligand	disco interacting protein 2 homolog A
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane Cytoplasmic Ribonucleoprotein Granule Extracellular Exosome	Nucleus Mitochondrion Cell Surface Membrane Dendritic Spine
	Molecular Function	Signaling Receptor Binding Protein Binding Identical Protein Binding	Acetate-CoA Ligase Activity Protein Binding
	Biological Process	Regulation Of Cytokine Production Adaptive Immune Response Defense Response Hyperosmotic Response Signal Transduction T Cell Costimulation Positive Regulation Of Activated T Cell Proliferation T Cell Activation B Cell Activation T Cell Receptor Signaling Pathway	Acetyl-CoA Biosynthetic Process Negative Regulation Of Gene Expression Dendritic Spine Morphogenesis Positive Regulation Of Peptidyl-lysine Acetylation
Pathways		Costimulation by the CD28 family
Drugs
Diseases
GWAS		Ankylosing spondylitis ( 23749187) Blood protein levels ( 30072576 29875488) Celiac disease ( 22057235 20190752) Cerebral amyloid deposition (PET imaging) ( 30361487) Crohn's disease ( 18587394 21102463) Eosinophil counts ( 32888494 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Inflammatory bowel disease ( 23128233) Left ventricular QRS voltage ( 27195777) Rheumatoid arthritis ( 30423114) Type 1 diabetes ( 25751624) Ulcerative colitis ( 21297633)	Anti-saccade response ( 29064472) Lymphocyte counts ( 32888494 27863252) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 32888494) Neutrophil count ( 32888494) Pulse pressure ( 30224653) White blood cell count ( 32888494)
Interacting Genes		1 interacting genes: ICOS	19 interacting genes: ADAMTSL4 CCDC33 CEP44 DAB2 DLX2 FAM214B GPATCH2L IQUB JMJD6 MBIP PSME3 PTPN3 SORBS3 STAC3 TLE5 TMCC2 TRIM39 TRIP13 ZBTB43
Entrez ID		23308	23181
HPRD ID		05757	07611
Ensembl ID		ENSG00000160223	ENSG00000160305
Uniprot IDs		A0N0L8 B7Z1W8 O75144	Q14689 Q96NX2
PDB IDs		6X4G 6X4T
Enriched GO Terms of Interacting Partners?
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