PPIP5K2 and SMARCC1

Data Source:
BioGRID (two hybrid)

		PPIP5K2	SMARCC1
Description		diphosphoinositol pentakisphosphate kinase 2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1
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GO Annotations	Cellular Component	Cytosol	Chromatin XY Body Nucleus Nucleoplasm Cytoplasm SWI/SNF Complex Protein-containing Complex NpBAF Complex NBAF Complex
	Molecular Function	Inositol-1,3,4,5,6-pentakisphosphate Kinase Activity Inositol Hexakisphosphate Kinase Activity Inositol Heptakisphosphate Kinase Activity Inositol Hexakisphosphate 5-kinase Activity ATP Binding Diphosphoinositol-pentakisphosphate Kinase Activity Inositol Hexakisphosphate 1-kinase Activity Inositol Hexakisphosphate 3-kinase Activity 5-diphosphoinositol Pentakisphosphate 3-kinase Activity	Transcription Coactivator Activity Protein Binding Nucleosomal DNA Binding Histone Binding Protein N-terminus Binding
	Biological Process	Inositol Metabolic Process Sensory Perception Of Sound Phosphorylation Inositol Phosphate Biosynthetic Process Inositol Phosphate Metabolic Process	Nucleosome Disassembly Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Nervous System Development Insulin Receptor Signaling Pathway Animal Organ Morphogenesis Prostate Gland Development Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process ATP-dependent Chromatin Remodeling Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Synthesis of pyrophosphates in the cytosol	RMTs methylate histone arginines RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Drugs
Diseases
GWAS		Insulinogenic index ( 23263489) Intelligence (MTAG) ( 29326435) Primary biliary cholangitis ( 26394269) Refractive error ( 32231278) Sleep duration (short sleep) ( 30846698) Type 2 diabetes ( 29632382) Type 2 diabetes (adjusted for BMI) ( 29632382)	Household income (MTAG) ( 31844048) Renal underexcretion gout ( 32238385) Systolic blood pressure ( 31928498)
Interacting Genes		3 interacting genes: POU2F1 POU6F2 SMARCC1	53 interacting genes: ADAMTSL4 ADD1 AKT1 CCNE1 CEBPB CFP CIDEB CYSRT1 EWSR1 FANCA FUS GATA1 GLRX3 GSTO2 ITCH KLF1 KRTAP13-3 KRTAP19-2 KRTAP21-2 KRTAP22-1 KRTAP26-1 KRTAP3-1 KRTAP3-2 KRTAP3-3 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP7-1 LRP2BP MGAT5B MSL1 MYC NCOA1 NEDD4 NONO NR3C1 OTX1 PLSCR1 PPIP5K2 PRMT5 PTH1R RELB SIN3A SLC15A2 SMARCA4 SMARCD3 SP1 SPATA12 TAF15 TRIM42 UFSP1 VGLL3 ZNF581
Entrez ID		23262	6599
HPRD ID		13802	03435
Ensembl ID		ENSG00000145725	ENSG00000173473
Uniprot IDs		A0A087WZV0 B4DGV1 O43314	Q58EY4 Q92922
PDB IDs		3T54 3T7A 3T99 3T9A 3T9B 3T9C 3T9D 3T9E 3T9F 4HN2 4NZM 4NZN 4NZO 4Q4C 4Q4D 5BYA 5BYB 5DGH 5DGI 6N5C	2YUS 5GJK 6KZ7
Enriched GO Terms of Interacting Partners?
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