ARL6IP1 and ARL6

Data Source:
HPRD (two hybrid)

		ARL6IP1	ARL6
Description		ADP ribosylation factor like GTPase 6 interacting protein 1	ADP ribosylation factor like GTPase 6
Image		No pdb structure
GO Annotations	Cellular Component	Sec61 Translocon Complex Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Integral Component Of Endoplasmic Reticulum Membrane	Cytoplasm Axonemal Microtubule Plasma Membrane Cilium Axoneme Membrane Membrane Coat Extracellular Exosome
	Molecular Function	Protein Binding Identical Protein Binding	GTPase Activity Protein Binding GTP Binding Phospholipid Binding Metal Ion Binding
	Biological Process	Positive Regulation Of L-glutamate Import Across Plasma Membrane Cotranslational Protein Targeting To Membrane Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Endoplasmic Reticulum Tubular Network Formation Regulation Of Endoplasmic Reticulum Tubular Network Organization Endoplasmic Reticulum Tubular Network Membrane Organization	Protein Targeting To Membrane Intracellular Protein Transport Determination Of Left/right Symmetry Visual Perception Wnt Signaling Pathway Vesicle-mediated Transport Melanosome Transport Protein Polymerization Cilium Assembly Protein Localization To Cilium
Pathways			BBSome-mediated cargo-targeting to cilium
Drugs
Diseases			Bardet-Biedl syndrome (BBS) Retinitis pigmentosa (RP)
GWAS		Refractive error ( 32231278)	Male infertility ( 19478329)
Interacting Genes		77 interacting genes: ACSF2 AQP6 ARL4D ARL6 C19orf18 CERT1 DIABLO EHD3 EMP1 F2RL1 FBXW7 FDFT1 FXR2 GAD2 GAS8 GOLPH3 GOLPH3L GORASP2 GPR151 GPR152 HGS HMGCL HSD17B13 INPP5K LMNA MCEMP1 MFSD14B MFSD5 MGST3 MIEF2 MTERF3 MYG1 NAPB NDRG4 NTAQ1 NUDT3 PAM16 PBX3 PICK1 PTPN9 RAB33A REEP6 RETREG3 RNF5 SDCBP SENP2 SHISA5 SHMT2 SLC10A6 SLC13A1 SLC35C2 SNX1 SNX10 SNX11 SNX12 SNX15 SNX2 SNX3 SNX4 SNX8 SPG21 STARD4 SUCLA2 TARS2 TFAM TMED8 TMEM14B TMEM248 TMEM258 TUFM UBE2I VMA21 WDFY2 WIPI2 YIPF4 ZFYVE21 ZNF391	6 interacting genes: ARL6IP1 ARL6IP4 ARL6IP5 ARL6IP6 ATL2 SEC61B
Entrez ID		23204	84100
HPRD ID		09641	10588
Ensembl ID		ENSG00000170540	ENSG00000113966
Uniprot IDs		A0A024QYV7 Q15041	Q9H0F7
PDB IDs			2H57
Enriched GO Terms of Interacting Partners?
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