ZZEF1 and PTPN4

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ZZEF1	PTPN4
Description		zinc finger ZZ-type and EF-hand domain containing 1	protein tyrosine phosphatase non-receptor type 4
Image		No pdb structure
GO Annotations	Cellular Component		Nucleoplasm Cytoplasm Cytosol Cytoskeleton Cytoplasmic Side Of Plasma Membrane
	Molecular Function	Calcium Ion Binding Zinc Ion Binding	Protein Tyrosine Phosphatase Activity Non-membrane Spanning Protein Tyrosine Phosphatase Activity Protein Binding Cytoskeletal Protein Binding
	Biological Process		Protein Dephosphorylation Peptidyl-tyrosine Dephosphorylation Cellular Response To Cytokine Stimulus
Pathways			Toll Like Receptor 4 (TLR4) Cascade Interleukin-37 signaling MECP2 regulates neuronal receptors and channels
Drugs			Alendronic acid
Diseases
GWAS		Anti-saccade response ( 29064472) Diastolic blood pressure ( 27841878) Functional impairment in major depressive disorder, bipolar disorder and schizophrenia ( 24039173) Glucose homeostasis traits ( 25524916) Heel bone mineral density ( 30598549) Platelet distribution width ( 32888494) Refractive error ( 32231278) Type 2 diabetes ( 28566273 30054458 30297969 29632382 30718926) Type 2 diabetes (adjusted for BMI) ( 29632382)	Lymphocyte counts ( 32888494) Monocyte count ( 32888494)
Interacting Genes		4 interacting genes: HSPB3 PHYHIP PTPN4 SKIL	12 interacting genes: ATRX CRK EEF1A1 EEF1G GRID2 GRIN2A KAT5 LPL MAPK12 PRSS1 TK1 ZZEF1
Entrez ID		23140	5775
HPRD ID		15906	01471
Ensembl ID		ENSG00000074755	ENSG00000088179
Uniprot IDs		O43149	P29074
PDB IDs			2CS5 2I75 2VPH 3NFK 3NFL 5EYZ 5EZ0
Enriched GO Terms of Interacting Partners?
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