KIF1B and KAZN

Data Source:
HPRD (in vivo)

		KIF1B	KAZN
Description		kinesin family member 1B	kazrin, periplakin interacting protein
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Kinesin Complex Microtubule Microtubule Associated Complex Synaptic Vesicle Axon Dendrite Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Neuron Projection Axon Cytoplasm	Cornified Envelope Nucleoplasm Cytosol Cytoskeleton Nuclear Speck Desmosome
	Molecular Function	Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATP-dependent Microtubule Motor Activity, Plus-end-directed ATPase Activity Kinesin Binding Kinase Binding Scaffold Protein Binding	Protein Binding
	Biological Process	Apoptotic Process Microtubule-based Movement Neuron-neuron Synaptic Transmission Neuromuscular Synaptic Transmission Anterograde Axonal Transport Positive Regulation Of Gene Expression Vesicle-mediated Transport Cytoskeleton-dependent Intracellular Transport Lysosome Localization Response To Rotenone Anterograde Neuronal Dense Core Vesicle Transport Retrograde Neuronal Dense Core Vesicle Transport Cellular Response To Nerve Growth Factor Stimulus Protein Localization To Cell Periphery	Cornification
Pathways		COPI-dependent Golgi-to-ER retrograde traffic Kinesins	Formation of the cornified envelope
Drugs
Diseases		Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
GWAS		Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Hand grip strength ( 29691431) Hematocrit ( 27863252) Hepatitis B virus-related hepatocellular carcinoma ( 29246937) Hepatocellular carcinoma ( 20676096) Lateral orbital frontal cortex volume ( 31530798) Mean platelet volume ( 22139419 32888494 27863252) Monocyte percentage of white cells ( 32888494) Multiple sclerosis ( 18997785) Neutrophil count ( 32888494) Platelet count ( 32888494) Virologic severity in Herpes simplex virus type 2 infection ( 29535370) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for BMI in non-smokers ( 28443625) White blood cell count ( 32888494)	Body mass index ( 28552196) Cerebral amyloid deposition in APOEe4 non-carriers (PET imaging) ( 26252872) Chronotype ( 30696823) Conotruncal heart defects (inherited effects) ( 28468790) Copper levels ( 26025379) Lean body mass ( 28552196) Logical memory (delayed recall) in Alzheimer's disease dementia ( 29274321) Mercury levels ( 26025379) Moderate-to-late spontaneous preterm birth ( 31194736) Non-response to antidepressants and depression ( 27622933) Polycystic ovary syndrome (reproductive subtype) ( 32574161) Triacylglyceride levels ( 31551469) Urinary albumin-to-creatinine ratio in diabetes ( 31511532) Weight ( 28552196)
Interacting Genes		22 interacting genes: ARHGAP1 BRCA1 CALM1 CHP1 CLIP4 CPEB1 DLG1 DLG2 DLG3 DLG4 DYSF EEF1A1 GIPC1 LAMTOR5 PATJ PGM1 POMP SIAH1 SNTA1 STARD13 TRIM55 YWHAG	12 interacting genes: ARID5A CLVS2 COIL DVL3 LMO2 LZTS1 LZTS2 PPL PSMA1 TNS4 TXN2 USP2
Entrez ID		23095	23254
HPRD ID		05818	11122
Ensembl ID		ENSG00000054523	ENSG00000189337
Uniprot IDs		O60333	Q674X7
PDB IDs		2EH0
Enriched GO Terms of Interacting Partners?
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