Description |
forkhead box O1 |
poly(ADP-ribose) polymerase 1 |
Image |
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Cellular Component |
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Molecular Function |
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Biological Process |
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- Negative Regulation Of Transcription By RNA Polymerase II
- Nucleotide-excision Repair, DNA Damage Recognition
- Nucleotide-excision Repair, DNA Duplex Unwinding
- Telomere Maintenance
- Double-strand Break Repair Via Homologous Recombination
- DNA Repair
- Nucleotide-excision Repair, Preincision Complex Stabilization
- Nucleotide-excision Repair, Preincision Complex Assembly
- Nucleotide-excision Repair, DNA Incision, 3'-to Lesion
- Nucleotide-excision Repair, DNA Incision, 5'-to Lesion
- Double-strand Break Repair
- Transcription By RNA Polymerase II
- Protein ADP-ribosylation
- Apoptotic Process
- Cellular Response To DNA Damage Stimulus
- Mitochondrion Organization
- Transforming Growth Factor Beta Receptor Signaling Pathway
- Response To Gamma Radiation
- Positive Regulation Of Cardiac Muscle Hypertrophy
- Regulation Of SMAD Protein Complex Assembly
- Protein Autoprocessing
- Peptidyl-serine ADP-ribosylation
- Peptidyl-glutamic Acid Poly-ADP-ribosylation
- Signal Transduction Involved In Regulation Of Gene Expression
- Macrophage Differentiation
- DNA ADP-ribosylation
- Mitochondrial DNA Metabolic Process
- Cellular Response To Insulin Stimulus
- Positive Regulation Of Intracellular Estrogen Receptor Signaling Pathway
- Nucleotide-excision Repair, DNA Incision
- Cellular Response To Oxidative Stress
- Cellular Response To UV
- Protein Modification Process
- DNA Damage Response, Detection Of DNA Damage
- Mitochondrial DNA Repair
- Regulation Of DNA Methylation
- Positive Regulation Of Transcription By RNA Polymerase II
- Regulation Of Catalytic Activity
- Positive Regulation Of Mitochondrial Depolarization
- Positive Regulation Of SMAD Protein Signal Transduction
- Protein Poly-ADP-ribosylation
- Protein Auto-ADP-ribosylation
- Global Genome Nucleotide-excision Repair
- Cellular Response To Zinc Ion
- Positive Regulation Of Protein Localization To Nucleus
- Positive Regulation Of Neuron Death
- Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway
- Positive Regulation Of Single Strand Break Repair
- Regulation Of Cellular Protein Localization
- Response To Aldosterone
- Negative Regulation Of Telomere Maintenance Via Telomere Lengthening
- Cellular Response To Amyloid-beta
- Positive Regulation Of Myofibroblast Differentiation
- Positive Regulation Of Double-strand Break Repair Via Homologous Recombination
- ATP Generation From Poly-ADP-D-ribose
- Positive Regulation Of Transcription Regulatory Region DNA Binding
- Negative Regulation Of ATP Biosynthetic Process
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Pathways |
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Drugs |
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Diseases |
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GWAS |
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Interacting Genes |
38 interacting genes:
AKT1
AR
CEBPB
CREBBP
CSNK1G1
CTNNB1
DACH1
DANCR
DYRK1A
ESR1
FHL2
FOXG1
G6PC1
GSK3B
HNF4A
HOXA10
HOXA5
LRPPRC
MDM2
MST1
NCOA1
PAK1
PARP1
PIK3R3
PITX1
PPARG
RARA
SET
SFN
SIRT1
SMAD3
SMAD4
SRC
THRB
TNS2
UBE2D2
YWHAG
YWHAZ
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105 interacting genes:
APTX
ATM
BCL2
BLID
BRD7
BUB3
CASP1
CASP3
CASP7
CASP8
CD86
CDKN1A
CENPA
CENPB
CREBBP
CTCF
CTSB
CTSG
DTX2
DUX4
E2F1
ERCC6
ERG
ETS1
FOXO1
GTF2F1
GZMB
GZMM
H1-0
H1-1
H1-2
H1-5
H2AC18
H2BC4
H3-3A
H3-4
H3C1
H4C3
HDAC1
HDAC3
HIPK2
HMGA1
HMGN1
HMGN2
HMGN4
HOXB7
HPF1
HSPA2
IKBKG
IL24
KAT2B
KLF5
LIG3
LZTR1
MACROH2A1
MED14
MED6
MORC2
MTA3
MYBL2
NAT10
NCL
NCOA6
NEDD8
NFATC1
NFKB1
NPM1
NRF1
OVOL2
PARP2
PARP3
PCNA
PIAS4
POLA1
POLA2
POU2F1
PRKDC
RARA
RASL10B
RBM14
RELA
RNF144A
RNF168
RPS3A
RXRA
SENP1
SENP3
SIRT1
SP1
SREK1
SUMO2
SUPT16H
SWAP70
TCF3
TCF4
THRSP
TP53
UBE2I
WRN
XRCC1
XRCC5
XRCC6
ZBTB16
ZBTB9
ZNF423
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Entrez ID |
2308 |
142 |
HPRD ID |
00645 |
01435 |
Ensembl ID |
ENSG00000150907
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ENSG00000143799
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Uniprot IDs |
Q12778
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A0A024R3T8
P09874
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PDB IDs |
3CO6
3CO7
3COA
4LG0
5DUI
6QVW
6QZR
6QZS
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1UK0
1UK1
1WOK
2COK
2CR9
2CS2
2DMJ
2JVN
2L30
2L31
2N8A
2RCW
2RD6
2RIQ
3GJW
3GN7
3L3L
3L3M
3OD8
3ODA
3ODC
3ODE
4AV1
4DQY
4GV7
4HHY
4HHZ
4L6S
4OPX
4OQA
4OQB
4PJT
4R5W
4R6E
4RV6
4UND
4UXB
4XHU
4ZZZ
5A00
5DS3
5HA9
5KPN
5KPO
5KPP
5KPQ
5WRQ
5WRY
5WRZ
5WS0
5WS1
5WTC
5XSR
5XST
5XSU
6BHV
6GHK
6NRF
6NRG
6NRH
6NRI
6NRJ
6NTU
6VKK
6VKO
6VKQ
6XVW
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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