Description |
TRAF2 and NCK interacting kinase |
SOS Ras/Rac guanine nucleotide exchange factor 1 |
Image |
|
|
Cellular Component |
|
|
Molecular Function |
|
|
Biological Process |
|
|
Pathways |
|
|
Drugs |
|
|
Diseases |
|
|
GWAS |
- Adolescent idiopathic scoliosis ( 28334814)
- Brain imaging in schizophrenia (dorsolateral prefrontal cortex interaction) ( 19023125)
- Brain morphology (min-P) ( 32665545)
- Brain morphology (MOSTest) ( 32665545)
- Cerebrospinal fluid AB1-42 levels ( 29274321)
- Change in serum metabolite levels ( 31636271)
- Change in serum metabolite levels (CMS) ( 31636271)
- Cortical surface area (MOSTest) ( 32665545)
- Estimated glomerular filtration rate after 1 year in renal transplantation (recipient effect) ( 30920136)
- Frontotemporal dementia (age at onset) ( 29724592)
- Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)
- Hip circumference adjusted for BMI ( 28552196)
- LDL cholesterol ( 21347282)
- Lymphocyte counts ( 32888494 27863252)
- Lymphocyte percentage of white cells ( 32888494)
- Monocyte count ( 32888494)
- Night sleep phenotypes ( 27126917)
- Response to antipsychotic treatment in schizophrenia ( 29503163)
- Subcortical volume (MOSTest) ( 32665545)
- Triglyceride levels ( 32154731)
- Type 2 diabetes ( 30054458)
|
- Aseptic loosening in total joint arthroplasty ( 31791832)
- Corticobasal degeneration ( 26077951)
- Sensorimotor dexterity ( 31596458)
|
Interacting Genes |
37 interacting genes:
ACTG1
AGTPBP1
AKAP9
ANK2
CLU
CNKSR2
DPYSL2
DPYSL3
DST
DYNC1H1
GOLGA4
GSE1
GSN
HARS1
MACF1
NCK1
NCOR2
NEDD4
NEFM
PAFAH1B1
PDE4DIP
PPM1E
PPP1R13B
RAP2A
SMARCE1
SMURF1
SNX6
SOS1
SPTBN1
SRGAP3
SYNE1
TIAM2
TNKS
TRAF2
TRIM2
TUBB2A
WWC1
|
56 interacting genes:
ABI1
ABI3
ANXA2
ATP6V1E1
BIN1
CAV1
CD19
CD2AP
COPS3
CRK
CRKL
CSF1R
EGFR
EPS8
EPS8L1
EPS8L2
ERBB2
ERBB3
ESR1
FGFR1
FRS2
FYN
GAB1
GRAP
GRB2
HCK
HDLBP
HRAS
ITSN1
ITSN2
LAT2
LCK
MAPK1
MAPK3
MUC1
NCK1
NCK2
PACSIN1
PACSIN3
PIK3R2
PLCG1
PTPN11
PTPN6
RANBP9
RIT2
RRAS
SH3BP5
SH3KBP1
SHC1
SIRPA
SNX18
SNX9
SPTAN1
TNIK
UBASH3A
ZAP70
|
Entrez ID |
23043 |
6654 |
HPRD ID |
18206 |
01681 |
Ensembl ID |
ENSG00000154310
|
ENSG00000115904
|
Uniprot IDs |
Q9UKE5
|
G5E9C8
Q07889
|
PDB IDs |
2X7F
5AX9
5CWZ
5D7A
6RA5
6RA7
|
1AWE
1BKD
1DBH
1NVU
1NVV
1NVW
1NVX
1Q9C
1XD2
1XD4
1XDV
2II0
3KSY
4NYI
4NYJ
4NYM
4URU
4URV
4URW
4URX
4URY
4URZ
4US0
4US1
4US2
5OVD
5OVE
5OVF
5OVG
5OVH
5OVI
5WFO
5WFP
5WFQ
5WFR
6BVI
6BVJ
6BVK
6BVL
6BVM
6CUO
6CUP
6CUR
6D55
6D56
6D59
6D5E
6D5G
6D5H
6D5J
6D5L
6D5M
6D5V
6D5W
6EPL
6EPM
6EPN
6EPO
6EPP
6F08
6SCM
6SFR
6V94
6V9F
6V9J
6V9L
6V9M
6V9N
6Y44
|
Enriched GO Terms of Interacting Partners? |
|
|
Tagcloud ? |
|
|
Tagcloud (Difference) ? |
|
|
Tagcloud (Intersection) ? |
|