RPIA and PCMT1

Data Source:
BioGRID (two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid)

		RPIA	PCMT1
Description		ribose 5-phosphate isomerase A	protein-L-isoaspartate (D-aspartate) O-methyltransferase
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Intracellular Membrane-bounded Organelle	Cytoplasm Cytosol Extracellular Exosome Extracellular Vesicle
	Molecular Function	Ribose-5-phosphate Isomerase Activity Protein Binding Identical Protein Binding Monosaccharide Binding	Protein-L-isoaspartate (D-aspartate) O-methyltransferase Activity Protein Binding Cadherin Binding
	Biological Process	D-ribose Metabolic Process Pentose-phosphate Shunt Pentose-phosphate Shunt, Non-oxidative Branch Ribose Phosphate Metabolic Process	Protein Methylation Protein Repair
Pathways		RPIA deficiency: failed conversion of R5P to RU5P RPIA deficiency: failed conversion of RU5P to R5P Pentose phosphate pathway	Protein repair
Drugs		4-phospho-L-threonic acid	S-adenosyl-L-homocysteine
Diseases
GWAS		Blood protein levels ( 30072576)	Brain morphology (MOSTest) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		19 interacting genes: ATPAF2 C14orf119 CENPP DDIT4L FOXP2 FXR2 GORASP2 HSPB8 LNX1 NIF3L1 NTAQ1 PCMT1 PICK1 PTPN11 RNF208 SDCBP STK16 TXN2 VTA1	12 interacting genes: AGTR1 APOA1 APOE CCR2 CHD3 CLP1 CREBBP CYSLTR2 IQCB1 RPIA TAAR1 VKORC1
Entrez ID		22934	5110
HPRD ID		01589	08908
Ensembl ID		ENSG00000153574	ENSG00000120265
Uniprot IDs		P49247	A0A0A0MRJ6 A0A3F2YNX8 B7Z972 F6S8N6 P22061
PDB IDs			1I1N 1KR5
Enriched GO Terms of Interacting Partners?
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