ZBTB1 and HEMGN

Data Source:
BioGRID (two hybrid)

		ZBTB1	HEMGN
Description		zinc finger and BTB domain containing 1	hemogen
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Centrosome Nuclear Body Nuclear Membrane	Nucleoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Protein Homodimerization Activity Metal Ion Binding Protein Heterodimerization Activity K63-linked Polyubiquitin Modification-dependent Protein Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of T Cell Mediated Immunity DNA Repair Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Cellular Response To DNA Damage Stimulus Translesion Synthesis B Cell Differentiation Positive Regulation Of Natural Killer Cell Differentiation T Cell Differentiation In Thymus Cellular Response To UV MRNA Transcription By RNA Polymerase II Innate Immune Response Positive Regulation Of T Cell Differentiation Thymus Development Protein Homooligomerization Positive Regulation Of Pro-T Cell Differentiation	Multicellular Organism Development Cell Differentiation Regulation Of Osteoblast Differentiation
Pathways
Drugs
Diseases
GWAS		Lymphocyte counts ( 32888494) Monocyte count ( 32888494) Neutrophil percentage of white cells ( 32888494) Urinary albumin-to-creatinine ratio ( 31630189)	Alopecia areata ( 25608926) Platelet count ( 27863252) Platelet distribution width ( 27863252) Plateletcrit ( 27863252) Quantitative traits ( 19197348) Thyroid cancer (Papillary, radiation-related) ( 20350937)
Interacting Genes		22 interacting genes: AKR7A2 AR EWSR1 FAM161A FANCG HEMGN KAT5 LZTR1 MAML3 MFAP1 NDN PCNA PIH1D2 PIM1 SCNM1 TRAF1 TRIM42 UBC UBE2I ZBTB25 ZNF417 ZNF572	34 interacting genes: AURKA AXIN2 BCL10 BUB1 CDH1 CTBP1 CTBP2 DCC DLC1 EGFR ENO1 EP300 FBXW7 FLCN GATA1 H2AC6 HMGA1 HSPA1A KAT6A KRAS MCC MED17 MLH3 NRAS ODC1 PTPRJ SMAD4 SP100 SRC THAP11 TLR2 TRAF3 WHRN ZBTB1
Entrez ID		22890	55363
HPRD ID		15688	17100
Ensembl ID		ENSG00000126804	ENSG00000136929
Uniprot IDs		Q9Y2K1	A0A024R162 Q9BXL5
PDB IDs
Enriched GO Terms of Interacting Partners?
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