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PUF60 and MIR140
Data Source:
BioGRID
(unspecified method)
PUF60
MIR140
Description
poly(U) binding splicing factor 60
microRNA 140
Image
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
Cell Junction
Extracellular Space
Molecular Function
DNA Binding
RNA Binding
Protein Binding
Identical Protein Binding
Cadherin Binding
RNA Polymerase II Complex Binding
MRNA 3'-UTR Binding
MRNA Binding Involved In Posttranscriptional Gene Silencing
Biological Process
Alternative MRNA Splicing, Via Spliceosome
Regulation Of Alternative MRNA Splicing, Via Spliceosome
MRNA Splicing, Via Spliceosome
MRNA Splice Site Selection
Apoptotic Process
Positive Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Positive Regulation Of BMP Signaling Pathway
Negative Regulation Of NF-kappaB Transcription Factor Activity
Negative Regulation Of Interleukin-6 Production
Negative Regulation Of Tumor Necrosis Factor Production
Negative Regulation Of Toll-like Receptor 4 Signaling Pathway
Gene Silencing By MiRNA
Defense Response To Bacterium
Cellular Response To Lipopolysaccharide
Cellular Response To Hypoxia
Negative Regulation Of Cytokine Production Involved In Inflammatory Response
Negative Regulation Of Vascular Endothelial Growth Factor Production
Cellular Response To Amyloid-beta
Negative Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
Negative Regulation Of Vascular Associated Smooth Muscle Cell Migration
Positive Regulation Of Vascular Associated Smooth Muscle Cell Apoptotic Process
Positive Regulation Of Vascular Associated Smooth Muscle Cell Differentiation Involved In Phenotypic Switching
Pathways
mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Body mass index (
26426971
)
Interacting Genes
101 interacting genes:
ARL8A
BORCS5
CACNA1A
CCNC
CD101
CHD3
CPEB2
DDIT4L
ERG
FBXO7
FHL2
FTHL17
FUBP1
H1-2
ID3
IQCN
KHDC4
MED28
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR122
MIR128-1
MIR128-2
MIR138-2
MIR140
MIR141
MIR143
MIR145
MIR155
MIR15A
MIR15B
MIR16-1
MIR16-2
MIR18A
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200A
MIR200B
MIR200C
MIR205
MIR20A
MIR20B
MIR21
MIR214
MIR221
MIR222
MIR25
MIR29A
MIR29B1
MIR29B2
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR429
MIR451A
MIR7-1
MIR7-2
MIR9-1
MIR9-3
MIR92A1
MIR92A2
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F2
MIRLET7G
MIRLET7I
PCBP1
PCBP3
PPP1R16A
PTBP2
QRICH1
RAD23B
RAP1GDS1
SAP30BP
SDCBP
SF1
SIAH1
SNRPF
SRSF11
TAF2
TH
U2AF2
UBE2I
UBTFL1
UPF2
VIM
YWHAG
ZG16
68 interacting genes:
ADARB1
AIMP1
APOBEC3B
C1QBP
CELF1
CELF2
CRTAP
CSTF1
DARS1
DDX1
DDX21
DDX3X
DDX49
EIF2AK2
EPRS1
FAM98A
FUS
G3BP2
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IARS1
IGF2BP1
IGF2BP2
IGF2BP3
KARS1
KNOP1
LARP7
LIN28A
LRPPRC
MARS1
MATR3
NOL6
NONO
NUDT21
PDCD11
PIKFYVE
PIP5K1A
PTBP1
PTBP3
PUF60
PUM1
PURA
QARS1
RARS1
RBFOX2
RBM14
RTCB
SF3B1
SF3B3
SFPQ
SYNCRIP
TAF15
TRA2A
TRA2B
UPF1
UTP20
YBX1
YBX3
Entrez ID
22827
406932
HPRD ID
18051
Ensembl ID
ENSG00000179950
ENSG00000208017
Uniprot IDs
Q9UHX1
PDB IDs
2DNY
2KXF
2KXH
2QFJ
3DXB
3UE2
3US5
3UWT
5KVY
5KW1
5KW6
5KWQ
6LUR
6SLO
Enriched GO Terms of Interacting Partners
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