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PUF60 and CHD3
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
PUF60
CHD3
Description
poly(U) binding splicing factor 60
chromodomain helicase DNA binding protein 3
Image
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
Cell Junction
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Centrosome
NuRD Complex
PML Body
Centriolar Satellite
Molecular Function
DNA Binding
RNA Binding
Protein Binding
Identical Protein Binding
Cadherin Binding
Transcription Regulatory Region Sequence-specific DNA Binding
DNA Binding
DNA Helicase Activity
RNA Binding
Helicase Activity
Protein Binding
ATP Binding
Zinc Ion Binding
ATPase Activity
Double-stranded DNA Helicase Activity
Nucleosome-dependent ATPase Activity
Biological Process
Alternative MRNA Splicing, Via Spliceosome
Regulation Of Alternative MRNA Splicing, Via Spliceosome
MRNA Splicing, Via Spliceosome
MRNA Splice Site Selection
Apoptotic Process
Negative Regulation Of Transcription By RNA Polymerase II
Chromatin Assembly Or Disassembly
Regulation Of Transcription, DNA-templated
Regulation Of Transcription By RNA Polymerase II
Spindle Organization
Centrosome Cycle
DNA Duplex Unwinding
ATP-dependent Chromatin Remodeling
Regulation Of Signal Transduction By P53 Class Mediator
Pathways
mRNA Splicing - Major Pathway
HDACs deacetylate histones
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
SUMOylation of chromatin organization proteins
Regulation of TP53 Activity through Acetylation
RNA Polymerase I Transcription Initiation
Regulation of PTEN gene transcription
Regulation of PTEN gene transcription
Potential therapeutics for SARS
Drugs
Diseases
GWAS
Ischemic stroke (
26089329
)
Macular thickness (
30535121
)
Prostate cancer (
29892016
)
Refractive error (
32231278
)
Stroke (
26089329
)
Interacting Genes
101 interacting genes:
ARL8A
BORCS5
CACNA1A
CCNC
CD101
CHD3
CPEB2
DDIT4L
ERG
FBXO7
FHL2
FTHL17
FUBP1
H1-2
ID3
IQCN
KHDC4
MED28
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR122
MIR128-1
MIR128-2
MIR138-2
MIR140
MIR141
MIR143
MIR145
MIR155
MIR15A
MIR15B
MIR16-1
MIR16-2
MIR18A
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200A
MIR200B
MIR200C
MIR205
MIR20A
MIR20B
MIR21
MIR214
MIR221
MIR222
MIR25
MIR29A
MIR29B1
MIR29B2
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR429
MIR451A
MIR7-1
MIR7-2
MIR9-1
MIR9-3
MIR92A1
MIR92A2
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F2
MIRLET7G
MIRLET7I
PCBP1
PCBP3
PPP1R16A
PTBP2
QRICH1
RAD23B
RAP1GDS1
SAP30BP
SDCBP
SF1
SIAH1
SNRPF
SRSF11
TAF2
TH
U2AF2
UBE2I
UBTFL1
UPF2
VIM
YWHAG
ZG16
96 interacting genes:
ACTR1B
ADH5
AIMP2
ATP5IF1
BARD1
BCL6
BHLHE40
C4orf17
CASP6
CASP8
CPE
CRCT1
CREB1
CREBBP
CSTF2
CTBP1
CTTN
ENTR1
FABP4
FBP2
FUBP1
GADD45A
GIT1
GPS2
GSK3B
H3C1
HABP4
HSD17B10
HSPH1
HTT
IK
IKZF1
IKZF3
IMMT
IVNS1ABP
KIF15
KPNA2
KPNB1
LRIF1
LUC7L2
MAFG
MAN2A2
MX1
MYB
NEFL
NR1H2
NR4A1
PAICS
PCMT1
PIAS4
PLK4
PRG2
PRPF40A
PSME1
PTN
PTPRS
PUF60
RAD51
RETREG2
RGS2
RIF1
RPL29
SAFB
SAT1
SATB1
SERBP1
SERF2
SGSM2
SIRT6
SKIL
SLC27A6
SPOP
SRRT
SUMO1
SUMO2
TAL1
TCERG1
THOC7
TNFRSF14
TNNT1
TP53
TP73
TRIM28
TRIM54
TSC22D1
TSPAN6
TTR
TXNDC9
UBA3
UBC
UBE2I
UROD
VIM
XRCC4
YAE1
ZHX1
Entrez ID
22827
1107
HPRD ID
18051
09071
Ensembl ID
ENSG00000179950
ENSG00000170004
Uniprot IDs
Q9UHX1
B3KWV4
Q12873
Q2TAZ1
PDB IDs
2DNY
2KXF
2KXH
2QFJ
3DXB
3UE2
3US5
3UWT
5KVY
5KW1
5KW6
5KWQ
6LUR
6SLO
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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