GPC4 and ABHD17A

Data Source:
BioGRID (two hybrid)

		GPC4	ABHD17A
Description		glypican 4	abhydrolase domain containing 17A, depalmitoylase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Golgi Lumen Plasma Membrane External Side Of Plasma Membrane Cell Surface Lysosomal Lumen Synapse Collagen-containing Extracellular Matrix Extracellular Exosome Glutamatergic Synapse Anchored Component Of Presynaptic Membrane	Plasma Membrane Endosome Membrane Membrane Nuclear Speck Dendritic Spine Intracellular Membrane-bounded Organelle Recycling Endosome Membrane Glutamatergic Synapse Anchored Component Of Postsynaptic Density Membrane Anchored Component Of Postsynaptic Recycling Endosome Membrane
	Molecular Function	Protein Binding Coreceptor Activity Involved In Wnt Signaling Pathway, Planar Cell Polarity Pathway	Protein Binding Palmitoyl-(protein) Hydrolase Activity
	Biological Process	Retinoid Metabolic Process Glycosaminoglycan Biosynthetic Process Glycosaminoglycan Catabolic Process Regulation Of Signal Transduction Wnt Signaling Pathway Cell Migration Wnt Signaling Pathway, Planar Cell Polarity Pathway Regulation Of Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Synaptic Membrane Adhesion Regulation Of Protein Localization To Membrane Regulation Of Presynapse Assembly	Protein Depalmitoylation Protein Phosphopantetheinylation Protein Localization To Membrane Regulation Of Postsynapse Organization Negative Regulation Of Protein Localization To Microtubule Positive Regulation Of Protein Localization To Endosome
Pathways		A tetrasaccharide linker sequence is required for GAG synthesis HS-GAG biosynthesis HS-GAG biosynthesis HS-GAG degradation Defective B4GALT7 causes EDS, progeroid type Defective B3GAT3 causes JDSSDHD Defective EXT2 causes exostoses 2 Defective EXT1 causes exostoses 1, TRPS2 and CHDS Defective B3GALT6 causes EDSP2 and SEMDJL1 Retinoid metabolism and transport	RAS processing
Drugs
Diseases
GWAS
Interacting Genes		10 interacting genes: ABHD17A ACP5 AKAP9 CCNC COL18A1 FGF2 PICK1 PTEN PTPRD PTPRF	13 interacting genes: BIRC2 EHMT2 GOLGA2 GPC4 HPGDS KRTAP5-9 MDFI PLSCR4 PNMA1 RGS20 TNIP1 TRAF1 TRIM27
Entrez ID		2239	81926
HPRD ID		02160	07475
Ensembl ID		ENSG00000076716	ENSG00000129968
Uniprot IDs		O75487	Q96GS6
PDB IDs
Enriched GO Terms of Interacting Partners?
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