ABHD17A and RGS20

Data Source:
BioGRID (two hybrid)

		ABHD17A	RGS20
Description		abhydrolase domain containing 17A, depalmitoylase	regulator of G protein signaling 20
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Endosome Membrane Membrane Nuclear Speck Dendritic Spine Intracellular Membrane-bounded Organelle Recycling Endosome Membrane Glutamatergic Synapse Anchored Component Of Postsynaptic Density Membrane Anchored Component Of Postsynaptic Recycling Endosome Membrane	Nucleus Cytoplasm Trans-Golgi Network Plasma Membrane
	Molecular Function	Protein Binding Palmitoyl-(protein) Hydrolase Activity	GTPase Activity GTPase Activator Activity Protein Binding
	Biological Process	Protein Depalmitoylation Protein Phosphopantetheinylation Protein Localization To Membrane Regulation Of Postsynapse Organization Negative Regulation Of Protein Localization To Microtubule Positive Regulation Of Protein Localization To Endosome	G Protein-coupled Receptor Signaling Pathway Regulation Of G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Signal Transduction Positive Regulation Of GTPase Activity
Pathways		RAS processing	G alpha (i) signalling events G alpha (i) signalling events G alpha (z) signalling events G alpha (z) signalling events
Drugs
Diseases
GWAS			Cerebrospinal fluid beta-site APP cleaving enzyme levels ( 29751835) Chronic obstructive pulmonary disease ( 32222710) Serum uric acid levels ( 29559957) Urinary albumin-to-creatinine ratio ( 26631737)
Interacting Genes		13 interacting genes: BIRC2 EHMT2 GOLGA2 GPC4 HPGDS KRTAP5-9 MDFI PLSCR4 PNMA1 RGS20 TNIP1 TRAF1 TRIM27	54 interacting genes: ABHD17A ADRB2 ALPP AQP1 CATSPER1 COL8A1 CRCT1 CREB5 FASLG GLRX3 GNAI1 GNAI2 GNAI3 GNAO1 GNAZ HOXA1 HRG HSPD1 INS KIF1A KLHL38 KRTAP4-2 KRTAP5-11 KRTAP5-6 KRTAP5-9 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3C LCE3D LCE3E LCE4A LCE5A LNX1 MAPKBP1 NECTIN2 NECTIN3 NEK8 NUFIP2 OSTM1 OTX1 PTGER3 PTPMT1 RANBP3 STMN2 TBC1D16 VASN
Entrez ID		81926	8601
HPRD ID		07475	06225
Ensembl ID		ENSG00000129968	ENSG00000147509
Uniprot IDs		Q96GS6	B3KSW4 H9NIM5 O76081
PDB IDs
Enriched GO Terms of Interacting Partners?
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