AK9 and PEA15

Data Source:
HPRD (two hybrid)

		AK9	PEA15
Description		adenylate kinase 9	proliferation and apoptosis adaptor protein 15
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Mitochondrion Cytosol Nuclear Membrane	Nucleoplasm Cytosol Microtubule Associated Complex
	Molecular Function	Adenylate Kinase Activity Nucleoside Diphosphate Kinase Activity ATP Binding Nucleoside Monophosphate Kinase Activity	Protein Binding
	Biological Process	DADP Phosphorylation DGDP Phosphorylation AMP Phosphorylation ATP Generation From ADP Nucleobase-containing Small Molecule Interconversion CDP Phosphorylation DAMP Phosphorylation CMP Phosphorylation DCMP Phosphorylation GDP Phosphorylation UDP Phosphorylation DCDP Phosphorylation TDP Phosphorylation	MAPK Cascade Activation Of MAPK Activity Apoptotic Process Carbohydrate Transport Response To Morphine Negative Regulation Of Glucose Import Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Pathways		Interconversion of nucleotide di- and triphosphates	RAF-independent MAPK1/3 activation RAF/MAP kinase cascade
Drugs
Diseases
GWAS		Lung cancer in ever smokers ( 28604730)
Interacting Genes		2 interacting genes: FBXL17 PEA15	40 interacting genes: ABCD4 AK9 AKT1 ATP1B3 CACYBP CAMK2G CASP8 CEP120 COPS5 DNAJB1 DYRK1A FADD HTRA2 KLHL12 L1CAM LUC7L2 MAPK1 MAPK3 MTIF3 OSBPL1A PANK4 PDE4DIP PDPK1 PGM1 PLD1 PLD2 PPP4R3A PRKCA PUS3 RAMAC RPS6KA3 RPSA RSL24D1 SNRPG SON TALDO1 TENT4B TERF2IP TJP1 TRAPPC13
Entrez ID		221264	8682
HPRD ID		12871	04579
Ensembl ID		ENSG00000155085	ENSG00000162734
Uniprot IDs		Q5TCS8	B1AKZ4 B1AKZ5 Q15121 Q96FS5
PDB IDs			4IZ5 4IZA 6P6B 6P6C
Enriched GO Terms of Interacting Partners?
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