SKA3 and SKA1

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		SKA3	SKA1
Description		spindle and kinetochore associated complex subunit 3	spindle and kinetochore associated complex subunit 1
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GO Annotations	Cellular Component	Kinetochore Condensed Chromosome Outer Kinetochore Centrosome Cytosol Spindle Microtubule Mitotic Spindle	Condensed Chromosome Outer Kinetochore Cytosol Spindle Microtubule Microtubule Cytoskeleton Mitotic Spindle
	Molecular Function	Protein Binding	Protein Binding Microtubule Binding
	Biological Process	Mitotic Cell Cycle Chromosome Segregation Regulation Of Microtubule Polymerization Or Depolymerization Cell Division	Mitotic Cell Cycle Chromosome Segregation Regulation Of Microtubule Polymerization Or Depolymerization Cell Division
Pathways			Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS			Itch intensity from mosquito bite adjusted by bite size ( 28199695) Large HDL particle concentration ( 29084231) Phospholipid levels in large HDL ( 29084231) Phospholipid levels in medium HDL ( 29084231)
Interacting Genes		7 interacting genes: APP AURKB LRRK2 NOL4 SKA1 SPC24 ZDHHC17	13 interacting genes: AURKB BLOC1S6 CCDC196 CCDC197 FAM9C NDC80 PSMC5 SKA2 SKA3 SNAPIN SPC24 SSC5D SYCE1
Entrez ID		221150	220134
HPRD ID		10706	12689
Ensembl ID		ENSG00000165480	ENSG00000154839
Uniprot IDs		Q8IX90	A0A024R294 Q96BD8
PDB IDs		4AJ5	4AJ5 4C9Y 4CA0
Enriched GO Terms of Interacting Partners?
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