SKA1 and CCDC197

		SKA1	CCDC197
Description		spindle and kinetochore associated complex subunit 1	coiled-coil domain containing 197
Image			No pdb structure
GO Annotations	Cellular Component	Condensed Chromosome Outer Kinetochore Cytosol Spindle Microtubule Microtubule Cytoskeleton Mitotic Spindle
	Molecular Function	Protein Binding Microtubule Binding	Protein Binding
	Biological Process	Mitotic Cell Cycle Chromosome Segregation Regulation Of Microtubule Polymerization Or Depolymerization Cell Division
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Itch intensity from mosquito bite adjusted by bite size ( 28199695) Large HDL particle concentration ( 29084231) Phospholipid levels in large HDL ( 29084231) Phospholipid levels in medium HDL ( 29084231)
Interacting Genes		13 interacting genes: AURKB BLOC1S6 CCDC196 CCDC197 FAM9C NDC80 PSMC5 SKA2 SKA3 SNAPIN SPC24 SSC5D SYCE1	18 interacting genes: BEX2 C1orf216 CCDC146 CCHCR1 CYTH4 DISC1 FMNL2 KRT3 KRT75 LCA5L NTAQ1 NXF1 RUNX1T1 SKA1 SMARCD1 TXN2 USHBP1 WASHC3
Entrez ID		220134	256369
HPRD ID		12689	12651
Ensembl ID		ENSG00000154839	ENSG00000175699
Uniprot IDs		A0A024R294 Q96BD8
PDB IDs		4AJ5 4C9Y 4CA0
Enriched GO Terms of Interacting Partners?
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