CBY2 and ARHGEF40

Data Source:
BioGRID (two hybrid)

		CBY2	ARHGEF40
Description		chibby family member 2	Rho guanine nucleotide exchange factor 40
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasmic Vesicle	Cytosol Plasma Membrane
	Molecular Function	Protein Binding	Guanyl-nucleotide Exchange Factor Activity
	Biological Process		Regulation Of Catalytic Activity
Pathways			NRAGE signals death through JNK Rho GTPase cycle G alpha (12/13) signalling events
Drugs
Diseases
GWAS			Hematocrit ( 32888494 27863252) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) Neuroblastoma (pediatric) ( 32599975) Pediatric nonalcoholic steatohepatitis ( 28918882) Plateletcrit ( 32888494) PR interval ( 32439900) Red blood cell count ( 32888494) Resting heart rate ( 27798624)
Interacting Genes		119 interacting genes: ACTN1 AIMP2 ARHGEF40 ARMC7 BEX3 C19orf44 C1orf109 CCDC146 CCDC185 CCDC187 CCDC198 CCDC57 CCHCR1 CCNG1 CDC23 CDC37 CDK18 CDK2 CEP44 CEP55 CEP57L1 CEP95 CHCHD3 CHIC2 CIBAR1 CKS1B CNNM3 CYTH4 DGCR6 DTNB DUSP14 DZIP1L EFCAB3 EIF4E2 ELOA ENKD1 FAM161A FANCG FARS2 FBXO17 FRS3 GADD45A GADD45GIP1 GOLGA2 GOLGA6A GOLGA6L2 GRAP2 HAUS1 HSF2BP ING5 ISCU KIAA0408 KIFC3 KLC3 LATS1 LENG1 LMO1 LMO2 LMO3 LNX1 MCRS1 MED28 METTL17 MLH1 MMAB MOS NDUFA5 NEK6 NINL NME7 NTAQ1 OIP5 PID1 PIN1 PLEKHN1 POLR1C PPFIA3 PPP1R13B PPP1R18 PRPF18 PRPF31 RCOR3 RNF6 RPL9 RTP5 RUNX1T1 SCNM1 SDCBP SH3RF2 SNAPC5 SSX3 SYCE1 SYT17 TCEA2 TCEANC TCHP TEX11 TRIM42 TRIML2 TSC2 TSGA10 TSGA10IP TUBGCP4 TXK TXLNA TXLNB USHBP1 ZC2HC1C ZFYVE26 ZMAT2 ZNF250 ZNF417 ZNF564 ZNF572 ZNF581 ZNF655 ZNF688 ZNF764 ZNF785	7 interacting genes: APP CBY2 GPSM2 MAPT MYCBP STC2 TAC1
Entrez ID		220082	55701
HPRD ID		14856	13335
Ensembl ID		ENSG00000174015	ENSG00000165801
Uniprot IDs		A0A140VJV5 Q8NA61	Q8TER5
PDB IDs
Enriched GO Terms of Interacting Partners?
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