ARHGEF40 and GPSM2

Data Source:
BioGRID (two hybrid)

		ARHGEF40	GPSM2
Description		Rho guanine nucleotide exchange factor 40	G protein signaling modulator 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane	Cytoplasm Centrosome Cytosol Cell Cortex Lateral Plasma Membrane Protein-containing Complex Mitotic Spindle Pole Lateral Cell Cortex Cell Cortex Region
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity	Nucleotide Binding GDP-dissociation Inhibitor Activity Protein Binding Protein C-terminus Binding Protein Domain Specific Binding Identical Protein Binding Protein Self-association Dynein Complex Binding
	Biological Process	Regulation Of Catalytic Activity	Establishment Of Mitotic Spindle Orientation Mitotic Spindle Organization G Protein-coupled Receptor Signaling Pathway Ran Protein Signal Transduction Regulation Of Catalytic Activity Cell Division Maintenance Of Centrosome Location Regulation Of Mitotic Spindle Organization Positive Regulation Of Protein Localization To Cell Cortex Positive Regulation Of Spindle Assembly
Pathways		NRAGE signals death through JNK Rho GTPase cycle G alpha (12/13) signalling events	G alpha (i) signalling events
Drugs
Diseases
GWAS		Hematocrit ( 32888494 27863252) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) Neuroblastoma (pediatric) ( 32599975) Pediatric nonalcoholic steatohepatitis ( 28918882) Plateletcrit ( 32888494) PR interval ( 32439900) Red blood cell count ( 32888494) Resting heart rate ( 27798624)	Fat distribution (HIV) ( 21897333)
Interacting Genes		7 interacting genes: APP CBY2 GPSM2 MAPT MYCBP STC2 TAC1	13 interacting genes: AGR2 ARHGEF40 GAS2L1 GLIS2 GNAI1 GNAI2 GNAI3 GNAO1 HRAS INSC LRRC8E NUMA1 WHRN
Entrez ID		55701	29899
HPRD ID		13335	06609
Ensembl ID		ENSG00000165801	ENSG00000121957
Uniprot IDs		Q8TER5	A0A024R0F8 B4DIF1 P81274
PDB IDs			3SF4 4WND 4WNE 4WNF 4WNG 5A6C 6HC2
Enriched GO Terms of Interacting Partners?
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