ABCB7 and RAP1GDS1

Data Source:
BioGRID (two hybrid)

		ABCB7	RAP1GDS1
Description		ATP binding cassette subfamily B member 7	Rap1 GTPase-GDP dissociation stimulator 1
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrial Inner Membrane Integral Component Of Membrane	Mitochondrion Endoplasmic Reticulum Cytosol Extracellular Exosome
	Molecular Function	Protein Binding ATP Binding Heme Transmembrane Transporter Activity ATPase Activity ATPase-coupled Transmembrane Transporter Activity	GTPase Activator Activity Protein Binding
	Biological Process	Cellular Iron Ion Homeostasis Heme Transport Transmembrane Transport	Vascular Associated Smooth Muscle Contraction Myosin Filament Assembly Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration Positive Regulation Of GTPase Activity Positive Regulation Of Mitochondrial Calcium Ion Concentration
Pathways		Mitochondrial ABC transporters Cytosolic iron-sulfur cluster assembly
Drugs
Diseases		Sideroblastic anemia, including: Pyridoxine-refractory autosomal recessive sideroblastic anemia (PRARSA); X-linked sideroblastic anemia (XLSA); X-linked sideroblastic anemia with ataxia (ASAT)
GWAS		Metabolite levels ( 23823483)	Biochemical measures ( 19260141) Response to fenofibrate (total cholesterol levels) ( 27002377)
Interacting Genes		3 interacting genes: APP FECH UBC	23 interacting genes: CDC42 DIRAS1 DIRAS2 DOC2A EGFR HRAS KIFAP3 KRAS MBIP NRAS PLEKHB1 PTPRF PUF60 RAB6B RAC1 RAP1A RAP2B RAP2C RHOA RNF19B RRAS RRAS2 ZNF451
Entrez ID		22	5910
HPRD ID		02137	11763
Ensembl ID		ENSG00000131269	ENSG00000138698
Uniprot IDs		A0A087WW65 A0A0S2Z2Z3 O75027	B3KNU0 P52306 Q6U7G8
PDB IDs			5XGC 5ZHX
Enriched GO Terms of Interacting Partners?
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