CAPN10 and EFNB1

Data Source:
BioGRID (two hybrid)

		CAPN10	EFNB1
Description		calpain 10	ephrin B1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Cytosol Plasma Membrane	Nucleus Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Membrane Raft Synapse Extracellular Exosome
	Molecular Function	SNARE Binding Calcium-dependent Cysteine-type Endopeptidase Activity Protein Binding Cytoskeletal Protein Binding	Protein Binding Ephrin Receptor Binding
	Biological Process	Proteolysis Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Actin Cytoskeleton Reorganization Positive Regulation Of Insulin Secretion Positive Regulation Of Intracellular Transport Cellular Response To Insulin Stimulus Positive Regulation Of Glucose Import Type B Pancreatic Cell Apoptotic Process Positive Regulation Of Type B Pancreatic Cell Apoptotic Process	Neural Crest Cell Migration Cell Adhesion Cell-cell Signaling Axon Guidance Embryonic Pattern Specification T Cell Costimulation Positive Regulation Of T Cell Proliferation Ephrin Receptor Signaling Pathway
Pathways		Degradation of the extracellular matrix	EPH-Ephrin signaling EPH-Ephrin signaling EPHB-mediated forward signaling EPHB-mediated forward signaling Ephrin signaling Ephrin signaling EPH-ephrin mediated repulsion of cells
Drugs
Diseases		Type II diabetes mellitus	Craniosynostosis, including: Pfeiffer syndrome; Apert syndrome; Crouzon syndrome; Jackson-Weiss syndrome; Beare-Stevenson syndrome; Muenke craniosynostosis; Saethre-Chotzen syndrome; Craniosynostosis Boston type; Antley-Bixler syndrome; Carpenter syndrome; Craniofrontonasal dysplasia; Noonan syndrome; Baller-Gerold syndrome
GWAS
Interacting Genes		5 interacting genes: EFNB1 FANCC FLOT1 PSMA7 SHD	18 interacting genes: ANKRD46 CAPN10 CUL3 DNAJC5 EPHA3 EPHB1 EPHB2 GRIP1 MYC NCK2 PICK1 PTPN13 RGS3 SDCBP SORBS1 SRC TIAM1 YWHAQ
Entrez ID		11132	1947
HPRD ID		05595	02072
Ensembl ID		ENSG00000142330	ENSG00000090776
Uniprot IDs		Q9HC96	P98172
PDB IDs			6THG
Enriched GO Terms of Interacting Partners?
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