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FBL and RUVBL2
Data Source:
BioGRID
(pull down)
FBL
RUVBL2
Description
fibrillarin
RuvB like AAA ATPase 2
Image
GO Annotations
Cellular Component
Fibrillar Center
Dense Fibrillar Component
Nucleus
Nucleoplasm
Chromosome
Nucleolus
Cajal Body
Membrane
Box C/D RNP Complex
Small-subunit Processome
Extracellular Exosome
Euchromatin
Swr1 Complex
Nucleus
Nucleoplasm
Cytoplasm
Centrosome
Cytosol
Membrane
Nuclear Matrix
Ino80 Complex
NuA4 Histone Acetyltransferase Complex
Extracellular Exosome
MLL1 Complex
R2TP Complex
Ribonucleoprotein Complex
Molecular Function
TFIID-class Transcription Factor Complex Binding
RNA Binding
Protein Binding
RRNA Methyltransferase Activity
ATPase Binding
Histone-glutamine Methyltransferase Activity
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Core Promoter Sequence-specific DNA Binding
TFIID-class Transcription Factor Complex Binding
DNA Helicase Activity
Transcription Corepressor Activity
Protein Binding
ATP Binding
Beta-catenin Binding
ATPase Activity
TBP-class Protein Binding
Chromatin DNA Binding
Identical Protein Binding
Protein Homodimerization Activity
5'-3' DNA Helicase Activity
ADP Binding
Unfolded Protein Binding
ATPase Binding
Biological Process
Box C/D RNA 3'-end Processing
Osteoblast Differentiation
RRNA Processing
RRNA Methylation
SnoRNA Localization
Histone Glutamine Methylation
Box C/D SnoRNP Assembly
DNA Repair
DNA Recombination
Chromatin Remodeling
Regulation Of Transcription By RNA Polymerase II
Protein Folding
Histone Acetylation
DNA Duplex Unwinding
Cellular Response To UV
Positive Regulation Of Histone Acetylation
Regulation Of Growth
Histone H4 Acetylation
Histone H2A Acetylation
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Establishment Of Protein Localization To Chromatin
Cellular Response To Estradiol Stimulus
Transcriptional Activation By Promoter-enhancer Looping
Negative Regulation Of Estrogen Receptor Binding
Negative Regulation Of Canonical Wnt Signaling Pathway
Positive Regulation Of Telomerase RNA Localization To Cajal Body
Pathways
rRNA modification in the nucleus and cytosol
Major pathway of rRNA processing in the nucleolus and cytosol
Telomere Extension By Telomerase
HATs acetylate histones
Drugs
Quercetin
Diseases
GWAS
Blood protein levels (
28240269
)
Interacting Genes
22 interacting genes:
DDX17
DDX5
ERG
H2AC20
KLF6
MAP3K14
PIN4
PRMT1
PRMT3
PRMT6
PRMT8
PSMB6
PTEN
RUVBL1
RUVBL2
SIRT7
SMN1
SMN2
SNRPN
TAF9
TBC1D17
ZNF792
31 interacting genes:
AGR2
APP
APPL1
APPL2
ATF2
BCL3
CCDC103
CDKN2A
CTNNB1
DNAJB4
DPCD
EHMT2
EP300
EXOSC10
FBL
FDFT1
HDAC1
HDAC4
LIG4
LNX1
MCPH1
MDM2
MYC
NDRG1
RUVBL1
STOM
TAF9
TBP
TERT
YWHAQ
YY1
Entrez ID
2091
10856
HPRD ID
00617
16070
Ensembl ID
ENSG00000105202
ENSG00000183207
Uniprot IDs
P22087
B3KNL2
Q9Y230
PDB IDs
2IPX
2CQA
2XSZ
3UK6
5OAF
6FO1
6H7X
6HTS
6IGM
6K0R
6QI8
6QI9
Enriched GO Terms of Interacting Partners
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