Wiki-MPM
About
Search
Browse
People
Funding
Updates
Search
CLN8 and GABARAPL2
Data Source:
BioGRID
(two hybrid)
CLN8
GABARAPL2
Description
CLN8 transmembrane ER and ERGIC protein
GABA type A receptor associated protein like 2
Image
No pdb structure
GO Annotations
Cellular Component
Mitochondrion
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Endoplasmic Reticulum-Golgi Intermediate Compartment
Integral Component Of Membrane
Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
Presynapse
Golgi Membrane
Autophagosome Membrane
Cytoplasm
Autophagosome
Endoplasmic Reticulum Membrane
Golgi Apparatus
Cytosol
Cytoplasmic Vesicle
Molecular Function
Protein Binding
Ceramide Binding
SNARE Binding
Protein Binding
Microtubule Binding
Ubiquitin Protein Ligase Binding
Beta-tubulin Binding
GABA Receptor Binding
ATPase Binding
Biological Process
Age-dependent Response To Oxidative Stress
Phospholipid Metabolic Process
Ceramide Metabolic Process
Lipid Transport
Mitochondrial Membrane Organization
Lysosome Organization
Nervous System Development
Visual Perception
Adult Walking Behavior
Cholesterol Metabolic Process
Associative Learning
Regulation Of Cell Size
Lipid Biosynthetic Process
Somatic Motor Neuron Differentiation
Protein Catabolic Process
Social Behavior
Negative Regulation Of Apoptotic Process
Cellular Protein Catabolic Process
Photoreceptor Cell Maintenance
Negative Regulation Of Proteolysis
Ceramide Biosynthetic Process
Musculoskeletal Movement
Neuromuscular Process Controlling Posture
Neuromuscular Process Controlling Balance
Glutamate Reuptake
Lipid Homeostasis
Retina Development In Camera-type Eye
Neurofilament Cytoskeleton Organization
Autophagosome Assembly
Autophagy Of Mitochondrion
Intra-Golgi Vesicle-mediated Transport
Autophagy
Cellular Response To Nitrogen Starvation
Protein Transport
Macroautophagy
Positive Regulation Of ATPase Activity
Protein Localization To Endoplasmic Reticulum
Autophagosome Maturation
Negative Regulation Of Proteasomal Protein Catabolic Process
Pathways
Macroautophagy
TBC/RABGAPs
Drugs
Diseases
Neuronal ceroid lipofuscinosis, including: Infantile Neuronal Ceroid Lipofuscinosis (INCL)/ Santavuori-Haltia Disease (CLN1); Late-Infantile Neuronal Ceroid Lipofuscinosis (LINCL)/ Jansky-Bielschowsky Disease (CLN2); Juvenile Neuronal Ceroid Lipofuscinosis (JNCL)/Batten Disease/ Spielmeyer-Vogt Disease (CLN3); Adult Neuronal Ceroid Lipofuscinosis (ANCL)/ Kufs Disease (CLN4); LINCL variant (CLN5, CLN6, CLN7, CLN8); Batten Disease variant (CLN9); Congenital NCL (CLN10)
Progressive myoclonic epilepsy (PME), including: Lafora disease (LBD); Unverricht-Lundborg disease (ULD); Neuronal ceroid lipofuscinoses (NCL); Type I sialidosis; Action myoclonus-renal failure syndrome (AMRF); Type III Gaucher disease (GD)
GWAS
Eye morphology (
29921221
)
Gaucher disease severity (
22388998
)
Systolic blood pressure (
30224653
)
Total cholesterol change in response to fenofibrate in statin-treated type 2 diabetes (
28736931
)
Blood protein levels (
30072576
)
Pancreatic cancer (
25086665
)
Interacting Genes
30 interacting genes:
ARL6IP5
BNIP3
BNIP3L
CD9
CYB5B
ERG28
FZD7
GABARAPL2
GPM6B
MTX1
NDRG2
PDIA6
PLP1
PLP2
PTPRN
RRP15
RTN4
SELENOK
SPCS2
STX8
TMEM107
TMEM11
TMEM128
TMEM134
TMEM147
TMEM14A
TUBB4A
UBC
YIPF6
ZUP1
89 interacting genes:
AAMP
AGTRAP
AHNAK2
AMBRA1
ANK2
APP
ARFGAP1
ATG13
ATG3
ATG4A
ATG4B
ATG4D
ATG7
BCL2L13
BNIP3L
BSDC1
CALCOCO1
CALCOCO2
CLN8
CUL3
DYNLL1
DYNLL2
EGFR
ERBB2
ERBB3
ERBB4
FUNDC1
GIMAP6
GOSR1
GPR37
HAP1
HSP90AB1
INSYN1
KASH5
KBTBD6
KBTBD7
KIAA1958
KIF16B
KLHL5
KRTAP10-7
KRTAP10-9
LRSAM1
LZTR1
MAP1LC3B
MCPH1
MEFV
MLX
NBR1
NEDD4
NPSR1
NSF
NUDT15
OPTN
OSBPL3
OSBPL7
PTPRA
RAP1A
RAP2A
RB1CC1
RCN2
RETREG1
RETREG3
RPS2
SCYL3
SGTA
SIK2
SMO
SQSTM1
TAX1BP1
TBC1D25
TBC1D5
TBC1D9
TBC1D9B
TEX264
TNIP1
TP53INP1
TP53INP2
TRIM21
TRIM32
TRIM45
TSR2
UBA5
ULK1
ULK2
VDR
WDFY3
YWHAZ
ZBTB2
ZNF774
Entrez ID
2055
11345
HPRD ID
06383
16246
Ensembl ID
ENSG00000182372
ENSG00000034713
Uniprot IDs
A0A024QZ57
Q9UBY8
P60520
PDB IDs
4CO7
6H8C
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?