PDILT and ERO1A

Data Source:
HPRD (in vivo, in vitro)

		PDILT	ERO1A
Description		protein disulfide isomerase like, testis expressed	endoplasmic reticulum oxidoreductase 1 alpha
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GO Annotations	Cellular Component	Endoplasmic Reticulum	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Membrane Dendrite Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Disulfide Isomerase Activity	Protein Disulfide Isomerase Activity Protein Binding Protein Disulfide Oxidoreductase Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On A Sulfur Group Of Donors, Disulfide As Acceptor
	Biological Process	Protein Folding Multicellular Organism Development Spermatid Development Cell Migration Protein Phosphopantetheinylation	Protein Folding Cellular Protein Modification Process Response To Temperature Stimulus Animal Organ Senescence Protein Phosphopantetheinylation Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline Protein Maturation By Protein Folding Extracellular Matrix Organization Endoplasmic Reticulum Unfolded Protein Response Cellular Response To Oxidative Stress Protein Folding In Endoplasmic Reticulum Response To Endoplasmic Reticulum Stress Cell Redox Homeostasis Brown Fat Cell Differentiation Chaperone Cofactor-dependent Protein Refolding Release Of Sequestered Calcium Ion Into Cytosol Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Cellular Response To Hypoxia
Pathways			Insulin processing Detoxification of Reactive Oxygen Species
Drugs
Diseases
GWAS		Adult body size ( 32376654) Blood urea nitrogen levels ( 31152163 29403010) Body mass index ( 29273807) Chronic kidney disease ( 31152163 20383146) Creatinine levels ( 31015462 29403010) Diastolic blood pressure ( 27841878) Diastolic blood pressure x smoking status (ever vs never) interaction (1df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Estimated glomerular filtration rate ( 31152163 31451708 30604766) Estimated glomerular filtration rate in diabetes ( 31451708) Estimated glomerular filtration rate in non-diabetics ( 31451708) Glomerular filtration rate ( 27588450 29403010) Kidney function decline traits ( 25493955) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Medication use (beta blocking agents) ( 31015401) Medication use (diuretics) ( 31015401) Urate levels ( 31578528) Urinary uromodulin levels ( 24578125) Urolithiasis ( 30975718)	Heel bone mineral density ( 30598549) Urine 6-bromotryptophan levels in chronic kidney disease ( 32572055)
Interacting Genes		1 interacting genes: ERO1A	12 interacting genes: APPBP2 EBF1 ERP44 GPX7 GPX8 LHX4 LINC01554 P4HB PDIA3 PDILT PELI2 RHOU
Entrez ID		204474	30001
HPRD ID		15111	13278
Ensembl ID		ENSG00000169340	ENSG00000197930
Uniprot IDs		Q8N807	Q96HE7
PDB IDs		4NWY 5XF7	3AHQ 3AHR
Enriched GO Terms of Interacting Partners?
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