CERS3 and PCBD2

Data Source:
BioGRID (two hybrid)

		CERS3	PCBD2
Description		ceramide synthase 3	pterin-4 alpha-carbinolamine dehydratase 2
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane	Cellular_component Nucleus
	Molecular Function	DNA Binding Protein Binding N-acyltransferase Activity Sphingosine N-acyltransferase Activity	Phenylalanine 4-monooxygenase Activity Protein Binding 4-alpha-hydroxytetrahydrobiopterin Dehydratase Activity Identical Protein Binding
	Biological Process	Epidermis Development Sphingolipid Biosynthetic Process Keratinocyte Differentiation Ceramide Biosynthetic Process Cornification	Tetrahydrobiopterin Biosynthetic Process Positive Regulation Of Transcription, DNA-templated
Pathways		Sphingolipid de novo biosynthesis
Drugs
Diseases
GWAS		Childhood body mass index ( 31752434) Cotinine glucuronidation ( 25293881)	Bulimia nervosa ( 23568457) Colorectal cancer ( 23263487) Height ( 28552196 18391951) Type 2 diabetes ( 24509480)
Interacting Genes		5 interacting genes: NEU1 ORMDL3 PCBD2 SLC29A2 SLC39A9	40 interacting genes: AATF APP ASCC2 BCAS2 BRF1 C1D CDC5L CENPK CERS3 CHAF1A FBXO7 GTF2E1 GUCD1 HES4 IRF2BP1 KCNIP3 KLC3 LGALS14 MAGEA11 MAGEA6 MED21 MED30 MED4 MED7 MET MRFAP1 PBXIP1 PCBD1 PHF14 PML RUNX1T1 SNW1 SPG21 SSX3 SSX5 STAT3 TAL2 TGIF2LY XBP1 ZZZ3
Entrez ID		204219	84105
HPRD ID		13961	17824
Ensembl ID		ENSG00000154227	ENSG00000132570
Uniprot IDs		Q8IU89	Q9H0N5
PDB IDs			4C45
Enriched GO Terms of Interacting Partners?
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