CERS3 and SLC29A2

Data Source:
BioGRID (two hybrid)

		CERS3	SLC29A2
Description		ceramide synthase 3	solute carrier family 29 member 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane	Nucleolus Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane Basolateral Plasma Membrane Nuclear Membrane Presynapse
	Molecular Function	DNA Binding Protein Binding N-acyltransferase Activity Sphingosine N-acyltransferase Activity	Neurotransmitter Transmembrane Transporter Activity Nucleoside Transmembrane Transporter Activity Purine Nucleoside Transmembrane Transporter Activity Uridine Transmembrane Transporter Activity
	Biological Process	Epidermis Development Sphingolipid Biosynthetic Process Keratinocyte Differentiation Ceramide Biosynthetic Process Cornification	Neurotransmitter Uptake Neurotransmitter Transport Adenine Transport Guanine Transport Nucleoside Transport Purine Nucleoside Transmembrane Transport Uridine Transport Adenosine Transport Hypoxanthine Transport Thymine Transport Pyrimidine-containing Compound Transmembrane Transport Neurotransmitter Reuptake Transport Across Blood-brain Barrier Nucleoside Transmembrane Transport
Pathways		Sphingolipid de novo biosynthesis	Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane
Drugs			Ethanol
Diseases
GWAS		Childhood body mass index ( 31752434) Cotinine glucuronidation ( 25293881)	Bipolar disorder ( 21926972) Serum uric acid levels ( 32514006)
Interacting Genes		5 interacting genes: NEU1 ORMDL3 PCBD2 SLC29A2 SLC39A9	19 interacting genes: ALOX5AP CERS3 CERS4 CREB3 ERGIC3 GJA4 GPR152 LAPTM4B PLPP5 SERINC2 SLC10A1 SLC10A6 TMEM237 TMEM242 TMEM33 TMEM86B TMX2 UBQLN1 UBQLN2
Entrez ID		204219	3177
HPRD ID		13961	03662
Ensembl ID		ENSG00000154227	ENSG00000174669
Uniprot IDs		Q8IU89	G5E943 Q14542 Q96FB2
PDB IDs
Enriched GO Terms of Interacting Partners?
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