PCBD2 and PBXIP1

Data Source:
BioGRID (two hybrid)

		PCBD2	PBXIP1
Description		pterin-4 alpha-carbinolamine dehydratase 2	PBX homeobox interacting protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Cellular_component Nucleus	Nucleus Cytosol Microtubule Membrane
	Molecular Function	Phenylalanine 4-monooxygenase Activity Protein Binding 4-alpha-hydroxytetrahydrobiopterin Dehydratase Activity Identical Protein Binding	Transcription Corepressor Activity Protein Binding
	Biological Process	Tetrahydrobiopterin Biosynthetic Process Positive Regulation Of Transcription, DNA-templated	Multicellular Organism Development Cell Differentiation Negative Regulation Of Transcription, DNA-templated Regulation Of Rho Guanyl-nucleotide Exchange Factor Activity
Pathways
Drugs
Diseases
GWAS		Bulimia nervosa ( 23568457) Colorectal cancer ( 23263487) Height ( 28552196 18391951) Type 2 diabetes ( 24509480)	Bipolar disorder ( 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Inflammatory bowel disease ( 27569725) Prostate cancer ( 23535732)
Interacting Genes		40 interacting genes: AATF APP ASCC2 BCAS2 BRF1 C1D CDC5L CENPK CERS3 CHAF1A FBXO7 GTF2E1 GUCD1 HES4 IRF2BP1 KCNIP3 KLC3 LGALS14 MAGEA11 MAGEA6 MED21 MED30 MED4 MED7 MET MRFAP1 PBXIP1 PCBD1 PHF14 PML RUNX1T1 SNW1 SPG21 SSX3 SSX5 STAT3 TAL2 TGIF2LY XBP1 ZZZ3	27 interacting genes: BRPF1 CAMLG CAPN2 CCDC85B CCNC DAXX DEF6 DPPA2 ESR1 GABARAPL1 GMCL1 GRB2 KRTAP10-6 LCA5L MDFI MDM2 MORF4L1 PCBD2 PPTC7 PRKAA2 SGTA TSNAX UBQLN1 UBQLN4 WASHC3 ZMYND8 ZZZ3
Entrez ID		84105	57326
HPRD ID		17824	17823
Ensembl ID		ENSG00000132570	ENSG00000163346
Uniprot IDs		Q9H0N5	B4E0K4 Q96AQ6
PDB IDs		4C45
Enriched GO Terms of Interacting Partners?
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