PEMT

Description		phosphatidylethanolamine N-methyltransferase
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Integral Component Of Membrane Brush Border Membrane Mitochondrial Membrane Sarcolemma Intracellular Membrane-bounded Organelle
	Molecular Function	Phosphatidyl-N-methylethanolamine N-methyltransferase Activity Phosphatidylethanolamine N-methyltransferase Activity Phosphatidylethanolamine Binding Phosphatidyl-N-dimethylethanolamine N-methyltransferase Activity
	Biological Process	Blastocyst Hatching Phosphatidylcholine Biosynthetic Process Sphingomyelin Biosynthetic Process Negative Regulation Of Cell Population Proliferation Methylation Response To Vitamin Response To Drug Response To Amino Acid Response To Ethanol S-adenosylhomocysteine Metabolic Process S-adenosylmethionine Metabolic Process Positive Regulation Of Lipoprotein Metabolic Process Positive Regulation Of Cold-induced Thermogenesis
Pathways		Synthesis of PC
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Apolipoprotein B levels ( 32203549) Coronary artery disease ( 24262325) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Coronary artery disease or ischemic stroke ( 24262325) Coronary artery disease or large artery stroke ( 24262325) Coronary heart disease ( 21378990) HDL cholesterol levels ( 32203549) Mean spheric corpuscular volume ( 32888494) Obsessive-compulsive symptoms ( 26859814) Triglyceride levels ( 32203549 32154731) Triglycerides ( 30275531) Waist-hip ratio ( 28552196 25673412) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for BMI (recessive genetic model) ( 30778226) Waist-to-hip ratio adjusted for body mass index ( 25673412)
Novel Interacting Genes		1 novel interacting genes: RAI1
Interacting Genes		4 interacting genes: AQP6 FCER1G SPP1 STOM
Entrez ID		10400
HPRD ID		03862
Ensembl ID		ENSG00000133027
Uniprot IDs		Q9UBM1
PDB IDs
Enriched GO Terms of Interacting Partners?
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