ANKS6 and VAMP4

Data Source:
BioGRID (two hybrid)

		ANKS6	VAMP4
Description		ankyrin repeat and sterile alpha motif domain containing 6	vesicle associated membrane protein 4
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Ciliary Inversin Compartment	Golgi Membrane Lysosome Endosome Golgi Apparatus Trans-Golgi Network Plasma Membrane Synaptic Vesicle Cell Surface Transport Vesicle Integral Component Of Synaptic Vesicle Membrane Clathrin-coated Vesicle Membrane SNARE Complex Trans-Golgi Network Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	In Utero Embryonic Development Kidney Development Determination Of Left/right Symmetry Heart Development	Microtubule Cytoskeleton Organization Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Synaptic Vesicle To Endosome Fusion SNARE Complex Assembly Golgi To Plasma Membrane Protein Transport Membrane Organization Golgi Ribbon Formation Regulation Of Synaptic Vesicle Endocytosis
Pathways			Retrograde transport at the Trans-Golgi-Network Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Body mass index ( 28892062)	Cognitive decline rate in late mild cognitive impairment ( 26252872) Hippocampal atrophy ( 25625606) Metabolite levels ( 23823483) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892)
Interacting Genes		19 interacting genes: AGTRAP APP BCL2L2 BET1 C1GALT1 C5 EMD EMP1 IGFBP5 MARCHF5 PITPNC1 RTP2 SMIM1 STRIT1 STX7 TMEM120B TMEM60 VAMP4 VEZT	45 interacting genes: ANKS6 AP1M1 AQP6 ARL13B BCL2L13 CISD2 CPLX4 CSNK2A1 CYB5R3 DNAJC5 EBP ELOVL4 ERGIC3 EVI2B FAM209A FAM210B GPR152 GPX8 KASH5 LDLRAD1 LEUTX MFF MGST3 MTIF3 PACS1 PSCA PTGES REEP4 RETREG3 SAR1A SEC11C SLC10A6 SNAP29 SSMEM1 STOM STX16 STX1A STX4 STX6 SYT2 TM4SF19 TMEM205 TMEM51 TMX2 TRIM54
Entrez ID		203286	8674
HPRD ID		18012	06070
Ensembl ID		ENSG00000165138	ENSG00000117533
Uniprot IDs		B3KXP1 Q68DC2	O75379 Q6IAZ3
PDB IDs		4NL9
Enriched GO Terms of Interacting Partners?
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