ENO2 and CD27

Data Source:
BioGRID (affinity chromatography technology)

		ENO2	CD27
Description		enolase 2	CD27 molecule
Image
GO Annotations	Cellular Component	Phosphopyruvate Hydratase Complex Photoreceptor Inner Segment Extracellular Space Cytosol Plasma Membrane Membrane Perikaryon Extracellular Exosome	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane
	Molecular Function	Magnesium Ion Binding Phosphopyruvate Hydratase Activity Protein Binding	Transmembrane Signaling Receptor Activity Protein Binding Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process
	Biological Process	Gluconeogenesis Glycolytic Process Regulation Of Vacuole Fusion, Non-autophagic Canonical Glycolysis	Cell Surface Receptor Signaling Pathway Immunoglobulin Mediated Immune Response Tumor Necrosis Factor-mediated Signaling Pathway Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Response To Ethanol Positive Regulation Of B Cell Differentiation Positive Regulation Of T Cell Differentiation Positive Regulation Of JNK Cascade Negative Regulation Of T Cell Apoptotic Process Extrinsic Apoptotic Signaling Pathway Positive Regulation Of NIK/NF-kappaB Signaling
Pathways		Glycolysis Gluconeogenesis	TNFs bind their physiological receptors
Drugs		2-Phosphoglycolic Acid
Diseases
GWAS			Crohn's disease ( 26192919)
Interacting Genes		25 interacting genes: A2M ACD AKT1 ANXA11 BMERB1 C6orf47 ENSA EXOC5 HABP4 HK1 HSF1 IL17B MAP4 MTNR1A NAT9 NDUFS7 POT1 SIGIRR SNUPN ST3GAL2 SUMO4 TERF1 TINF2 TUBA4A UBE2C	8 interacting genes: ACTN2 CD70 CIB1 SIVA1 TRAF2 TRAF3 TRAF5 UHRF2
Entrez ID		2026	939
HPRD ID		00573	01723
Ensembl ID		ENSG00000111674	ENSG00000139193
Uniprot IDs		P09104 Q6FHV6	P26842
PDB IDs		1TE6 2AKM 2AKZ 3UCC 3UCD 3UJE 3UJF 3UJR 3UJS 4ZA0 4ZCW 5EU9 5IDZ 5TD9 5TIJ	5TL5 5TLJ 5TLK
Enriched GO Terms of Interacting Partners?
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