PRIMPOL and NAV1

Data Source:
BioGRID (two hybrid)

		PRIMPOL	NAV1
Description		primase and DNA directed polymerase	neuron navigator 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Replication Fork Mitochondrial Matrix	Cytoplasm Microtubule Microtubule Cytoskeleton Axon Initial Segment
	Molecular Function	Chromatin Binding DNA-directed DNA Polymerase Activity DNA Primase Activity Protein Binding Zinc Ion Binding Manganese Ion Binding
	Biological Process	Mitochondrial DNA Replication DNA Replication, Synthesis Of RNA Primer Response To UV Translesion Synthesis Replication Fork Processing Error-prone Translesion Synthesis Mitochondrial DNA Repair R-loop Disassembly	Microtubule Bundle Formation Neuron Migration Nervous System Development
Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 28240269)	BMI (adjusted for smoking behaviour) ( 28443625) BMI in non-smokers ( 28443625) Body mass index ( 26961502 25673413 29273807 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Body mass index in physically active individuals ( 28448500) Calcific aortic valve stenosis ( 32141789) Celiac disease ( 23936387) Diastolic blood pressure ( 30578418) HDL cholesterol levels ( 32203549) Heel bone mineral density ( 30598549) Insomnia symptoms (never/rarely vs. sometimes/usually) ( 30804566) Insomnia symptoms (never/rarely vs. usually) ( 30804566) Neurociticism ( 29500382) Obesity-related traits ( 23251661) Optic disc size ( 31809533) Pulse pressure ( 27841878 30578418) Sleep duration (short sleep) ( 30846698) Waist circumference ( 25673412)
Interacting Genes		5 interacting genes: CDKN2D MPP1 NAV1 PSMA1 RPA1	10 interacting genes: APC APP DDIT4L GCC1 KIFAP3 KRT31 MAPRE1 PRIMPOL RSRC2 TBC1D4
Entrez ID		201973	89796
HPRD ID		08742	10113
Ensembl ID		ENSG00000164306	ENSG00000134369
Uniprot IDs		A0A5S6SZ32 Q96LW4	Q8NEY1
PDB IDs		5L2X 5N85 5N8A
Enriched GO Terms of Interacting Partners?
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