NAV1 and KIFAP3

Data Source:
BioGRID (two hybrid)

		NAV1	KIFAP3
Description		neuron navigator 1	kinesin associated protein 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Microtubule Microtubule Cytoskeleton Axon Initial Segment	Condensed Nuclear Chromosome Endoplasmic Reticulum Golgi Apparatus Centrosome Cytosol Spindle Microtubule Cilium Axoneme Microtubule Cytoskeleton Kinesin II Complex Photoreceptor Connecting Cilium Ciliary Transition Zone Ciliary Basal Body Ciliary Tip Periciliary Membrane Compartment
	Molecular Function		Protein Binding Kinesin Binding Protein Phosphatase Binding Intraciliary Transport Particle B Binding
	Biological Process	Microtubule Bundle Formation Neuron Migration Nervous System Development	Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Microtubule-based Process Microtubule-based Movement Signal Transduction Negative Regulation Of Cell Population Proliferation Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Intraciliary Transport Involved In Cilium Assembly Negative Regulation Of Apoptotic Process Cilium Organization Positive Regulation Of Calcium-dependent Cell-cell Adhesion Protein-containing Complex Assembly Plus-end-directed Vesicle Transport Along Microtubule
Pathways			Translocation of SLC2A4 (GLUT4) to the plasma membrane MHC class II antigen presentation Intraflagellar transport COPI-dependent Golgi-to-ER retrograde traffic Kinesins Kinesins
Drugs
Diseases
GWAS		BMI (adjusted for smoking behaviour) ( 28443625) BMI in non-smokers ( 28443625) Body mass index ( 26961502 25673413 29273807 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Body mass index in physically active individuals ( 28448500) Calcific aortic valve stenosis ( 32141789) Celiac disease ( 23936387) Diastolic blood pressure ( 30578418) HDL cholesterol levels ( 32203549) Heel bone mineral density ( 30598549) Insomnia symptoms (never/rarely vs. sometimes/usually) ( 30804566) Insomnia symptoms (never/rarely vs. usually) ( 30804566) Neurociticism ( 29500382) Obesity-related traits ( 23251661) Optic disc size ( 31809533) Pulse pressure ( 27841878 30578418) Sleep duration (short sleep) ( 30846698) Waist circumference ( 25673412)	Acute anterior uveitis in ankylosing spondylitis ( 32492107) Adverse response to drug ( 30420678) Amyotrophic lateral sclerosis ( 19451621) Atrial fibrillation ( 28416818) L-selectin levels ( 25576479) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		10 interacting genes: APC APP DDIT4L GCC1 KIFAP3 KRT31 MAPRE1 PRIMPOL RSRC2 TBC1D4	33 interacting genes: APC AR C19orf44 CCSER2 DHX37 DISC1 GTSE1 HOXB5 KANK2 KIF3B MAP3K10 MAP3K11 MARK2 MEST MINK1 MOS MYPOP NAA10 NAA11 NAV1 NCF2 NIPSNAP3A NUDT21 PARD6G PEX19 PRNP RAP1GDS1 RBFOX1 RBM14 RPGR RTP5 SMC3 SRC
Entrez ID		89796	22920
HPRD ID		10113	03499
Ensembl ID		ENSG00000134369	ENSG00000075945
Uniprot IDs		Q8NEY1	Q92845
PDB IDs
Enriched GO Terms of Interacting Partners?
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