ARHGAP27 and RETREG3

Data Source:
BioGRID (affinity chromatography technology)

		ARHGAP27	RETREG3
Description		Rho GTPase activating protein 27	reticulophagy regulator family member 3
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Membrane	Integral Component Of Membrane Protein-containing Complex
	Molecular Function	GTPase Activator Activity SH3 Domain Binding	Protein Binding
	Biological Process	Receptor-mediated Endocytosis Signal Transduction Regulation Of GTPase Activity Positive Regulation Of GTPase Activity	Positive Regulation Of Neuron Projection Development Reticulophagy
Pathways		Rho GTPase cycle
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406) Asthma ( 30929738) Asthma (childhood onset) ( 30929738) Asthma onset (childhood vs adult) ( 30929738) Brain morphology (MOSTest) ( 32665545) Cognitive function ( 28093568) Cortical surface area (global PC1) ( 32198502) General cognitive ability ( 29844566) General factor of neuroticism ( 30867560) Hemoglobin levels ( 32327693) Male-pattern baldness ( 28196072) Mean platelet volume ( 32888494) Neuroticism ( 29255261) Parkinson's disease ( 28892059) Refractive error ( 32231278) Systemic lupus erythematosus ( 29848360)	Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892)
Interacting Genes		3 interacting genes: CDC42 RAC1 SH3KBP1	109 interacting genes: ABHD16A ACSL5 AGPAT4 AGTRAP ANKRD46 ARL6IP1 ARPC3 ATP6V0C BET1 BNIP1 C16orf92 C1GALT1 C4orf3 CCDC167 CCL4L2 CDIPT CDS1 CLCA4 CMTM3 CMTM5 CMTM7 CSGALNACT2 CYB5B CYP4F2 DERL1 DHRSX ERG28 FAXDC2 FKBP8 FUNDC2 GABARAPL1 GABARAPL2 GIMAP5 GOSR2 HMOX2 HTATIP2 IFITM3 JAGN1 LEMD1 LPAR3 LPCAT2 LRCH4 MAL2 MALL MAP1LC3A MCRS1 MFF MOB2 MOSPD3 NRM ORMDL2 ORMDL3 OTULINL PKMYT1 PLP2 PLPP6 PNLIPRP1 PRAF2 RABAC1 REEP6 RUSF1 SCD SEC22A SENP2 SERP2 SFT2D1 SFXN3 SLC30A3 SLC39A6 SMCO4 SMIM1 STAP1 STX5 STX7 STX8 SYNGR1 TBRG4 TCEA2 TECR TMEM100 TMEM11 TMEM120B TMEM128 TMEM176A TMEM18 TMEM203 TMEM218 TMEM222 TMEM237 TMEM239 TMEM243 TMEM254 TMEM31 TMEM42 TMEM60 TMEM65 TMPPE TPRG1 TSNARE1 TSPO2 UBIAD1 VAMP1 VAMP3 VAMP4 VAMP5 VAPA VAPB YIPF1 YIPF6
Entrez ID		201176	162427
HPRD ID		12477	14108
Ensembl ID		ENSG00000159314	ENSG00000141699
Uniprot IDs		E9PIR1 E9PNT2 Q6ZUM4 Q8N2Y9	K7EQI9 Q86VR2
PDB IDs		3PP2
Enriched GO Terms of Interacting Partners?
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