RETREG3 and SLC30A3

Data Source:
BioGRID (two hybrid)

		RETREG3	SLC30A3
Description		reticulophagy regulator family member 3	solute carrier family 30 member 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane Protein-containing Complex	Cytoplasm Lysosomal Membrane Endosome Late Endosome Plasma Membrane Integral Component Of Plasma Membrane Synaptic Vesicle Membrane Integral Component Of Synaptic Vesicle Membrane Late Endosome Membrane Neuron Projection Hippocampal Mossy Fiber Hippocampal Mossy Fiber To CA3 Synapse Glutamatergic Synapse
	Molecular Function	Protein Binding	Zinc Ion Transmembrane Transporter Activity Protein Binding ABC-type Zinc Transporter Activity
	Biological Process	Positive Regulation Of Neuron Projection Development Reticulophagy	Response To Zinc Ion Positive Regulation Of Transport Regulation Of Sequestering Of Zinc Ion Zinc Ion Transmembrane Transport Zinc Ion Import Into Synaptic Vesicle
Pathways			Zinc efflux and compartmentalization by the SLC30 family
Drugs
Diseases
GWAS		Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892)	Metabolite levels ( 23823483)
Interacting Genes		109 interacting genes: ABHD16A ACSL5 AGPAT4 AGTRAP ANKRD46 ARL6IP1 ARPC3 ATP6V0C BET1 BNIP1 C16orf92 C1GALT1 C4orf3 CCDC167 CCL4L2 CDIPT CDS1 CLCA4 CMTM3 CMTM5 CMTM7 CSGALNACT2 CYB5B CYP4F2 DERL1 DHRSX ERG28 FAXDC2 FKBP8 FUNDC2 GABARAPL1 GABARAPL2 GIMAP5 GOSR2 HMOX2 HTATIP2 IFITM3 JAGN1 LEMD1 LPAR3 LPCAT2 LRCH4 MAL2 MALL MAP1LC3A MCRS1 MFF MOB2 MOSPD3 NRM ORMDL2 ORMDL3 OTULINL PKMYT1 PLP2 PLPP6 PNLIPRP1 PRAF2 RABAC1 REEP6 RUSF1 SCD SEC22A SENP2 SERP2 SFT2D1 SFXN3 SLC30A3 SLC39A6 SMCO4 SMIM1 STAP1 STX5 STX7 STX8 SYNGR1 TBRG4 TCEA2 TECR TMEM100 TMEM11 TMEM120B TMEM128 TMEM176A TMEM18 TMEM203 TMEM218 TMEM222 TMEM237 TMEM239 TMEM243 TMEM254 TMEM31 TMEM42 TMEM60 TMEM65 TMPPE TPRG1 TSNARE1 TSPO2 UBIAD1 VAMP1 VAMP3 VAMP4 VAMP5 VAPA VAPB YIPF1 YIPF6	28 interacting genes: AP3B1 AP3D1 AP3S1 CD40 CGRRF1 DNAJC5 ELOVL4 FCRL3 GJA8 GOLM1 GPR152 GPR42 GPX8 HSD17B13 LMNA NAALADL2 OCIAD1 RETREG3 RNF19B RTN3 SCN3B SGPL1 SLC10A6 SLC30A8 SLC34A2 SLC35C2 TMEM14B TMEM242
Entrez ID		162427	7781
HPRD ID		14108	11924
Ensembl ID		ENSG00000141699	ENSG00000115194
Uniprot IDs		K7EQI9 Q86VR2	B4DXX8 Q99726
PDB IDs
Enriched GO Terms of Interacting Partners?
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