RETREG3 and GOSR2

Data Source:
BioGRID (two hybrid)

		RETREG3	GOSR2
Description		reticulophagy regulator family member 3	golgi SNAP receptor complex member 2
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane Protein-containing Complex	Golgi Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol ER To Golgi Transport Vesicle Membrane Membrane Integral Component Of Membrane SNARE Complex Late Endosome Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
	Molecular Function	Protein Binding	SNARE Binding SNAP Receptor Activity Protein Binding
	Biological Process	Positive Regulation Of Neuron Projection Development Reticulophagy	Protein Targeting To Vacuole Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Intra-Golgi Vesicle-mediated Transport Golgi To Vacuole Transport IRE1-mediated Unfolded Protein Response Retrograde Transport, Endosome To Golgi COPII Vesicle Coating Vesicle Fusion With Golgi Apparatus
Pathways			COPII-mediated vesicle transport XBP1(S) activates chaperone genes Cargo concentration in the ER COPI-mediated anterograde transport Intra-Golgi traffic
Drugs
Diseases
GWAS		Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892)	Aortic root size ( 28394258) Atrial fibrillation ( 29892015) Blood pressure ( 21909110) Blood urea nitrogen levels ( 31152163 29403010) Body mass index ( 26426971) Cleft lip with or without cleft palate ( 28054174) Coronary artery disease ( 29212778 33020668) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Electrocardiographic traits ( 32602732) Feeling guilty ( 29500382) Feeling worry ( 29500382) Hemoglobin levels ( 32327693) Idiopathic pulmonary fibrosis ( 29066090) Ischemic stroke ( 29930801) Mean arterial pressure ( 27618448) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Medication use (calcium channel blockers) ( 31015401) Myocardial infarction ( 30226566) Nonsyndromic cleft lip with cleft palate ( 28232668) Orofacial clefts ( 28054174) Pulse pressure ( 27841878 28739976 30578418) QRS duration ( 27577874 30012220 21076409) QT interval ( 29874175) Systolic blood pressure ( 28135244 27841878 21909115 28739976 27618447 27618452 30578418)
Interacting Genes		109 interacting genes: ABHD16A ACSL5 AGPAT4 AGTRAP ANKRD46 ARL6IP1 ARPC3 ATP6V0C BET1 BNIP1 C16orf92 C1GALT1 C4orf3 CCDC167 CCL4L2 CDIPT CDS1 CLCA4 CMTM3 CMTM5 CMTM7 CSGALNACT2 CYB5B CYP4F2 DERL1 DHRSX ERG28 FAXDC2 FKBP8 FUNDC2 GABARAPL1 GABARAPL2 GIMAP5 GOSR2 HMOX2 HTATIP2 IFITM3 JAGN1 LEMD1 LPAR3 LPCAT2 LRCH4 MAL2 MALL MAP1LC3A MCRS1 MFF MOB2 MOSPD3 NRM ORMDL2 ORMDL3 OTULINL PKMYT1 PLP2 PLPP6 PNLIPRP1 PRAF2 RABAC1 REEP6 RUSF1 SCD SEC22A SENP2 SERP2 SFT2D1 SFXN3 SLC30A3 SLC39A6 SMCO4 SMIM1 STAP1 STX5 STX7 STX8 SYNGR1 TBRG4 TCEA2 TECR TMEM100 TMEM11 TMEM120B TMEM128 TMEM176A TMEM18 TMEM203 TMEM218 TMEM222 TMEM237 TMEM239 TMEM243 TMEM254 TMEM31 TMEM42 TMEM60 TMEM65 TMPPE TPRG1 TSNARE1 TSPO2 UBIAD1 VAMP1 VAMP3 VAMP4 VAMP5 VAPA VAPB YIPF1 YIPF6	51 interacting genes: APP AQP6 ARF1 ARL13B BET1 BLCAP CREB3L1 CYB561 CYBRD1 EBP ELOVL4 ELOVL5 FAM174A FAM209A FATE1 GOLGA8EP GOLGA8F GPR152 GPR42 GPX8 HIBADH HSD17B13 IER3IP1 JAGN1 KASH5 LEUTX LIME1 LMNA MARCHF8 MFF MFSD14B MFSD5 NAPA PELI1 RETREG3 RIC3 RNF19B SLC10A1 SLC10A6 SPAG4 STX1A STX4 STX5 TLCD4 TM4SF19 TMCO5A TMEM106A TMEM106C TMEM205 TMEM35A USO1
Entrez ID		162427	9570
HPRD ID		14108	04937
Ensembl ID		ENSG00000141699	ENSG00000108433
Uniprot IDs		K7EQI9 Q86VR2	A0A1W2PQE0 A0A1W2PQM3 A0A1W2PR02 A0A1W2PRL0 I3NI02 O14653
PDB IDs			3EG9
Enriched GO Terms of Interacting Partners?
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